Results 71 to 80 of about 601,157 (307)

Biallelic Inactivation of NSD1 Associated With Carcinogenesis in Sotos Syndrome

open access: yes
Pediatric Blood &Cancer, EarlyView.
Nicholas A. Borja   +8 more
wiley   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Physiological and transcriptomic comparisons shed light on the cold stress response mechanisms of Dendrobium spp

open access: yesBMC Plant Biology
Background Dendrobium spp. comprise a group of tropical orchids with ornamental and medicinal value. Dendrobium spp. are sensitive to low temperature, and the underlying cold response regulatory mechanisms in this group are unclear.
Zhiyuan Li   +6 more
doaj   +1 more source

Genetic engineering to enhance mercury phytoremediation [PDF]

open access: yesCurrent Opinion in Biotechnology, 2009
Most phytoremediation studies utilize merA or merB genes to modify plants via the nuclear or chloroplast genome, expressing organomercurial lyase and/or mercuric ion reductase in the cytoplasm, endoplasmic reticulum or within plastids. Several plant species including Arabidopsis, tobacco, poplar, rice, Eastern cottonwood, peanut, salt marsh grass and ...
Ruiz, Oscar N., Daniell, Henry
openaire   +4 more sources

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Repugnance as Performance Error: The Role of Disgust in Bioethical Intuitions [PDF]

open access: yes, 2016
An influential argument in bioethics involves appeal to disgust, calling on us to take it seriously as a moral guide (e.g. Kass, Miller, Kahan). Some argue, for example, that genetic enhancement, especially via human reproductive cloning, is repellant or
May, Joshua
core  

Self-adaptive GA, quantitative semantic similarity measures and ontology-based text clustering [PDF]

open access: yes, 2008
As the common clustering algorithms use vector space model (VSM) to represent document, the conceptual relationships between related terms which do not co-occur literally are ignored.
Li, Chenghua   +3 more
core   +1 more source

Enhancing sustainable development through plant genetics

open access: yesNature Reviews Genetics, 2023
In April 2023, scholars and experts met members of the US Congress for the Aspen Institute Congressional Program conference in Bellagio, Italy, to discuss strategies to ensure global food security. Building on her perspective from this meeting, Pamela Ronald highlights the role that plant genetics can have in achieving these goals.
openaire   +4 more sources

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Comparative proteomic analysis provides insight into a complex regulatory network of taproot formation in radish (Raphanus sativus L.)

open access: yesHorticulture Research, 2018
Root vegetables: tapping into root thickening for improved yields An investigation into the proteins and genes responsible for taproot thickening in radish could help improve yields of root vegetables.
Yang Xie   +7 more
doaj   +1 more source

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