Results 211 to 220 of about 735,632 (337)

Editorial: Methods in applied genetic epidemiology 2022. [PDF]

Front Genet
Guo Q, Foley CN, Kuncheva Z.
europepmc   +1 more source

Genetic epidemiology: an 'enlightened narrative'? [PDF]

, 2004
George Davey Smith
openalex   +1 more source

Spatio‐Temporal Proteomic Landscape Reveals Early Warning Signals of Esophageal Squamous Cell Carcinoma Progression

Advanced Science, EarlyView.
This study constructs a proteomic atlas of esophageal squamous cell carcinoma (ESCC) progression using esophageal biopsy samples. It identifies moderate dysplasia as the critical turning stage and a seven‐protein panel for early detection. Functionally, GBP6 loss promotes ESCC progression via cell cycle and epithelial‐mesenchymal transition (EMT ...
Xumiao Li, Jie Yuan, Min Gao, Jibin Liu, Qinqin Wang, Yaqi Zhang, Mingtao Cao, Xiaolin Hu, Hui Yang, Jun Li, Chen Li, Xiaoguang Li, Hui Wang   +12 more
wiley   +1 more source

Low-Density Lipoprotein Cholesterol as a Protective Factor in COPD and Implications for Statin Therapy: A Multi-Omics Genetic Epidemiology Study. [PDF]

Int J Chron Obstruct Pulmon Dis
Du T, Cao J, Dai Z, Xie X, Zhang G, Li Y, Chen B, Xu T, Feng J.   +8 more
europepmc   +1 more source

Hypertensive Diseases in Pregnancy and Kidney Function Later in Life: The Genetic Epidemiology Network of Arteriopathy (GENOA) Study. [PDF]

Mayo Clin Proc, 2022
Oshunbade AA, Lirette ST, Windham BG, Shafi T, Hamid A, Gbadamosi SO, Tin A, Yimer WK, Tibuakuu M, Clark D, Kamimura D, Lutz EA, Mentz RJ, Fox ER, Butler J, Butler KR, Garovic VD, Turner ST, Mosley TH, Hall ME.   +19 more
europepmc   +1 more source

Biomechanical Phenotyping Reveals Unique Mechanobiological Signatures of Early‐Onset Colorectal Cancer

Advanced Science, EarlyView.
This study identifies a unique physical signature of colorectal cancer in younger adults: their tissues are mechanically stiffer than those in older patients with the same cancer. Furthermore, stromal remodeling in early‐onset colorectal cancer promotes epithelial mechanotransduction and proliferation, showing how mechanical alterations in the tissue ...
Nicole C. Huning, Munir H. Buhaya, Victor V. Nguyen, Afeefah Khazi‐Syed, Haider A. Ali, Adil Khan, Angela Fan, Robert C. Fisher, Zhikai Chi, Indu Raman, Guangchun Chen, Chengsong Zhu, Mengxi Yu, Andrew R. Jamieson, Sara Roccabianca, Victor D. Varner, Cheryl M. Lewis, Emina H. Huang, Jacopo Ferruzzi   +18 more
wiley   +1 more source

Genetic epidemiology of amyotrophic lateral sclerosis in Cyprus: a population-based study. [PDF]

Sci Rep
Mitsi E, Votsi C, Koutsou P, Georghiou A, Christodoulou CC, Kleopa K, Zamba-Papanicolaou E, Christodoulou K, Nicolaou P.   +8 more
europepmc   +1 more source

Genetic epidemiology of blood type, disease and trait variants, and genome-wide genetic diversity in over 11,000 domestic cats. [PDF]

PLoS Genet, 2022
Anderson H, Davison S, Lytle KM, Honkanen L, Freyer J, Mathlin J, Kyöstilä K, Inman L, Louviere A, Chodroff Foran R, Forman OP, Lohi H, Donner J.   +12 more
europepmc   +1 more source

PFOS Disrupts Oocyte Maturation and Early Embryonic Development via Ovarian FOXK1 O‐GlcNAcylation in Mice

Advanced Science, EarlyView.
Perfluorooctane sulfonate (PFOS) exposure disrupts oocyte maturation and early embryonic development. This study elucidates the mechanism by which enhanced O‐GlcNAcylation of FOXK1 underlies the PFOS‐induced reduction of progesterone levels in granulosa cells and the disturbance of follicular microenvironment.
Shuwen Han, Qin Yuan, Zhu Wu, Yaohui Fang, Hong Qian, Jiale Zhu, Yuchen Zhang, Ke Deng, Liangliang Su, Haibo Xu, Haotian Shu, Yiming Gong, Qiaoqiao Xu, Guizhen Du, Di Wu, Yun Fan, Chuncheng Lu   +16 more
wiley   +1 more source

The Genetic Epidemiology of Joint Shape and the Development of Osteoarthritis. [PDF]

Calcif Tissue Int, 2021
Wilkinson JM, Zeggini E.
europepmc   +1 more source