Results 231 to 240 of about 2,745,050 (303)

A Facial Foundation Model for Clinical Biomarker Prediction and Real‐World Mobile Deployment

Advanced Science, EarlyView.
MedicalFaceFound is a facial foundation model developed through three‐stage progressive pre‐training, adapting representations from general vision to facial structure and clinical phenotypes. Using a single facial image, it estimates 62 biomarkers across multiple physiological systems and supports downstream risk prediction for cardiovascular ...
Tingfeng Xu, Huixuan Xu, Li Lin, Fei Wang, Yaodong Ding, Shuangqiao Liao, Xingyu Chen, Jichen Wen, Hongqiang Zhao, Jing Hao, Weixiang Zhao, Gong Zhang, Shiguang Shan, Yong Zeng, Hu Han, Minxian Wang   +15 more
wiley   +1 more source

Compound Abrus cantoniensis Extract Alleviates AFB1‐Induced Liver Injury by Regulating PI3K‐AKT Pathway and Gut Microbiota/Butyrate Metabolism

Advanced Science, EarlyView.
ACCE has a good alleviating effect on AFB1‐induced liver injury, and this alleviating effect is related to the PI3K‐AKT pathway regulated by ACCE and the butyrate metabolism of gut microbiota. ABSTRACT Aflatoxin B1 (AFB1) is a potent hepatotoxin commonly ingested through contaminated food. Abrus cantoniensis Hance, a traditional Chinese medicinal herb,
Hongjie Hu, Ming cheng, Shiqi Zheng, Huixin Liu, Xiaofang Wei, Wenwen Yang, Hongchun Yang, Liuyang Yuan, Li Jiang, Jie Chen, Linglong Zhao, Yanchao Guo, Hongbin Si   +12 more
wiley   +1 more source

Spinal muscular atrophy genetic epidemiology and the case for premarital genomic screening in Arab populations. [PDF]

Commun Med (Lond)
Rabea F, El Naofal M, Chekroun I, Khalaf M, Zaabi NA, AlZaabi K, ElHalik M, Dash S, El Saba Y, Ali A, Abraham S, Fathi K, Shekhy J, Aswad SG, Elbashir H, Alkuraya F, Loney T, Alsheikh-Ali A, Khayat AA, Abou Tayoun A.   +19 more
europepmc   +1 more source

Integrated Multi‐Omics Reveals Cellular States and Microenvironmental Remodeling in Coexisting DCIS and IDC

Advanced Science, EarlyView.
Coexisting DCIS and IDC samples are profiled using spatial transcriptomics, single‐cell RNA sequencing, and single‐cell DNA sequencing. Integrative multi‐omics analysis reveals distinct malignant epithelial and microenvironmental features between DCIS and IDC, which are further validated using Xenium and multiplex immunohistochemistry.
Ning Zhang, Tong Wan, Siyue Zhang, Yunzhen Jiang, Peng Su, Jixin Liu, Zhitong Chen, Jie Hao, Haoyu Wang, Bing Chen, Wenjing Zhao, Lijuan Wang, Tao Xing, Qihuang Zhang, Ulf Schmitz, Zhiyong Ding, Nicola Crosetto, Bingqiang Liu, Qifeng Yang   +18 more
wiley   +1 more source

Antimicrobial Susceptibility and Genetic Epidemiology of Extended-Spectrum β-Lactamase-Positive Enterobacterales Clinical Isolates in Central Poland. [PDF]

Int J Mol Sci
Brauncajs M, Bielec F, Macieja A, Machnicki P, Pastuszak-Lewandoska D.   +4 more
europepmc   +1 more source

Oral Recombinant Human Collagen III Protects Gastric Mucosa via G‐Quadruplex‐Mediated Activation of the Pla2g4a‐Prostaglandin Axis

Advanced Science, EarlyView.
Orally administered recombinant human type III collagen protects the gastric mucosa from ethanol‐induced injury by coordinating redox homeostasis, epithelial barrier repair, and arachidonic acid–prostaglandin metabolism. Gastric digestion releases the pentapeptide GPAEF, which interacts with the Pla2g4a promoter G‐quadruplex in a structure‐dependent ...
Xinyue Lan, Qiu Dai, Yanhui Wang, Jiaxuan Gu, Chengyun Wang, Weicheng Xu, Xinru Gao, Jiageng Cheng, Wentao Geng, Xiaowen Wu, Haihang Li, Xiaoyun He, Shengwei Fu, Longjiao Zhu, Wentao Xu   +14 more
wiley   +1 more source

Gut Microbial Topology and Metabolic Signatures Associated With Colorectal Neoplasia

Advanced Science, EarlyView.
The gut microbiota organizes into two robust association patterns linked to colorectal neoplasia risk. Topological shifts in microbial networks are associated with metabolite alterations and may shape host responses during disease development. ABSTRACT Alterations of gut microbial communities impact health.
Kai Song, Youwen Qin, Jiahui Luo, Liping Liu, Chenyu Luo, Yinbin Qiu, Yiyi Zhong, Huanzi Zhong, Kui Wu, Meng Ni, Dong Wu, Min Dai, Shida Zhu, Hongda Chen   +13 more
wiley   +1 more source

Eating Disorders and Parkinson’s Disease - 2: Population Burden, Genetic Epidemiology and Shared Genomics

Bergen AW, Makowski C, Garvin M, Cil G, Krueger A, McGlone K, Litvan I, Kaye WF.   +7 more
europepmc   +1 more source