Results 1 to 10 of about 17,950,735 (256)

HIBLUP: an integration of statistical models on the BLUP framework for efficient genetic evaluation using big genomic data

Nucleic Acids Research, 2023
Human diseases and agricultural traits can be predicted by modeling a genetic random polygenic effect in linear mixed models. To estimate variance components and predict random effects of the model efficiently with limited computational resources has ...
Lilin Yin, Haohao Zhang, Zhenshuang Tang, Dong Yin, Yuhua Fu, Xiaohui Yuan, Xinyun Li, Xiaolei Liu, S. Zhao   +8 more
semanticscholar   +1 more source

Genetic evaluation including intermediate omics features.

Genetics, 2021
In animal and plant breeding and genetics, there has been an increasing interest in intermediate omics traits, such as metabolomics and transcriptomics, which mediate the effect of genetics on the phenotype of interest. For inclusion of such intermediate
O. F. Christensen, V. Börner, L. Varona, A. Legarra   +3 more
semanticscholar   +1 more source

Diversity of Linum genetic resources in global genebanks: from agro-morphological characterisation to novel genomic technologies – a review

Frontiers in Nutrition, 2023
Linseed or flaxseed is a well-recognized nutritional food with nutraceutical properties owing to high omega-3 fatty acid (α-Linolenic acid), dietary fiber, quality protein, and lignan content. Currently, linseed enjoys the status of a ‘superfood’ and its
Vikender Kaur, Mamta Singh, Dhammaprakash Pandhari Wankhede, Kavita Gupta, Sapna Langyan, Jayaraman Aravind, Boopathi Thangavel, Shashank Kumar Yadav, Sanjay Kalia, Kuldeep Singh, Ashok Kumar   +10 more
doaj   +1 more source

Genetic evaluation in children with short stature

Current opinion in pediatrics, 2021
Purpose of review Short stature is a common clinical manifestation in children. Yet, a cause is often unidentifiable in the majority of children with short stature by a routine screening approach.
Elaine Zhou, Benjamin R. Hauser, Y. Jee
semanticscholar   +1 more source

Proteomics-derived basal biomarker DNA-PKcs is associated with intrinsic subtype and long-term clinical outcomes in breast cancer

npj Breast Cancer, 2021
Precise biomarkers are needed to guide better diagnostics and therapeutics for basal-like breast cancer, for which DNA-dependent protein kinase catalytic subunit (DNA-PKcs) has been recently reported by the Clinical Proteomic Tumor Analysis Consortium as
Karama Asleh, Nazia Riaz, Angela S. Cheng, Dongxia Gao, Samuel C. Y. Leung, Meenakshi Anurag, Torsten O. Nielsen   +6 more
doaj   +1 more source

Heterogeneity of triple negative breast cancer: Current advances in subtyping and treatment implications

Journal of Experimental & Clinical Cancer Research, 2022
As the field of translational ‘omics has progressed, refined classifiers at both genomic and proteomic levels have emerged to decipher the heterogeneity of breast cancer in a clinically-applicable way.
Karama Asleh, Nazia Riaz, Torsten O. Nielsen   +2 more
doaj   +1 more source

Integrated omics approaches for flax improvement under abiotic and biotic stress: Current status and future prospects

Frontiers in Plant Science, 2022
Flax (Linum usitatissimum L.) or linseed is one of the important industrial crops grown all over the world for seed oil and fiber. Besides oil and fiber, flax offers a wide range of nutritional and therapeutic applications as a feed and food source owing
Bindu Yadav, Vikender Kaur, Om Prakash Narayan, Shashank Kumar Yadav, Ashok Kumar, Dhammaprakash Pandhari Wankhede   +5 more
doaj   +1 more source

Melatonin Secretion in Regulating the Circadian Rhythms of Reproduction in Goose (Anser cygnoides)

Agriculture, 2023
Circadian rhythms affect the physiology and behavior of most organisms. The ovulation–laying cycle of poultry exhibits evident rhythmic patterns. However, the underlying biological mechanism has remained unclear.
Qiang Bao, Di Liu, Yujiao Guo, Wang Gu, Zhengfeng Cao, Yu Zhang, Yang Zhang, Qi Xu, Guohong Chen   +8 more
doaj   +1 more source

Influence of bound dodecanoic acid on the reconstitution of albumin nanoparticles from a lyophilized state

Scientific Reports, 2021
The development of reference standards for nanoparticle sizing allows for cross laboratory studies and effective transfer of particle sizing methodology. To facilitate this, these reference standards must be stable upon long-term storage.
Christian C. E. Luebbert, Rola Mansa, Raisa Rahman, Zygmunt J. Jakubek, Grant E. Frahm, Shan Zou, Michael J. W. Johnston   +6 more
doaj   +1 more source

Substantial Genetic Progress in the International Apis mellifera carnica Population Since the Implementation of Genetic Evaluation

Insects, 2020
Simple Summary The Apis mellifera carnica subspecies of the honeybee is known for its gentleness and good honey yield. In the early 20th century, systematic breeding efforts began.
A. Hoppe, M. Du, R. Bernstein, F. Tiesler, M. Kärcher, K. Bienefeld   +5 more
semanticscholar   +1 more source