Results 151 to 160 of about 8,430,932 (306)

A deregression-based approach to integrate multitrait information into a single pooled phenotype for genetic evaluation. [PDF]

Genet Sel Evol
Markey A, Gengler N.
europepmc   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

FEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav, Bogdan I. Florea, Sebastian Geibel   +2 more
wiley   +1 more source

Genetic Evaluation Practices in Living Kidney Donor Candidates. [PDF]

Kidney Int Rep
Caliskan Y, Oto OA, Alhamad T, Yazici H, Velioglu A, Yildiz A, Radunovic D, Garg N, Kousios A, Ural Z, Mejia C, Viklicky O, Sayer J, Jittirat A, Ma MB, Madken M, Ozkurt S, Daloul R, Trujillo H, Soliman K, Castellano G, Turkmen A, Alfieri C, Manzoor A, Lee B, Thomas CP, Mannon RB, Lentine KL.   +27 more
europepmc   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Comment on "Incidental Colorectal Adenomas in Adolescents: Clinical Management, Genetic Evaluation, and Surveillance". [PDF]

J Gastroenterol Hepatol
Wang LJ, Yao YH, Li SN, Liu L.
europepmc   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

Two Cases of <i>ASXL3</i>-Related Bainbridge-Ropers Syndrome: Clinical and Genetic Evaluation. [PDF]

Case Rep Genet
Baş ŞS, Yeter B, Elcioglu NH.
europepmc   +1 more source

Genetic evaluation of calving ease for Walloon Holstein dairy cattle.

, 2013
Calving complications have an incidence on the economic profitability of dairy herds. In the Walloon Region of Belgium, calving ease data recording is being done on voluntary basis since 2000. This allows now the implementation of a genetic evaluation of
Vanderick, Sylvie, Troch, Thibault, Glorieux, Géry, Gengler, Nicolas, Gillon, Alain, Faux, Pierre   +5 more
core  

Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers

FEBS Letters, EarlyView.
Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui, Agnes Banreti, Armelle L. Ernst, Guillaume Leseigneur, Uwe J. Meierhenrich   +4 more
wiley   +1 more source

Genetic Evaluation and Pregnancy Outcomes in Foetuses With Overgrowth at a Tertiary Referral Center. [PDF]

J Cell Mol Med
Wu X, Shen Q, Xie X, Chen Y, Liang B, Wang M, Guo D, Lin N, Xu L.   +8 more
europepmc   +1 more source