Results 71 to 80 of about 56,733 (259)

Predicting the minimum horizontal principal stress using genetic expression programming and borehole breakout data

Journal of Rock Mechanics and Geotechnical Engineering
As a critical component of the in situ stress state, determination of the minimum horizontal principal stress plays a significant role in both geotechnical and petroleum engineering. To this end, a gene expression programming (GEP) algorithm-based model,
Rui Zhang, Jian Zhou
doaj   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

Hyper-Heuristic Coevolution of Machine Assignment and Job Sequencing Rules for Multi-Objective Dynamic Flexible Job Shop Scheduling

IEEE Access, 2019
Nowadays, real-time scheduling is one of the key issues in cyber-physical system. In real production, dispatching rules are frequently used to react to disruptions.
Yong Zhou, Jian-Jun Yang, Lian-Yu Zheng
doaj   +1 more source

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

FEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

Prediction of wear life of shield disc cutter in complex formations based on genetic programming

Gong-kuang zidonghua, 2018
In process of shield tunneling in complex formation, wear of disc cutter is extremely serious and service life is hard to predict, and influence factors of the disc cutter wear are multi-dimensional and uncertain.
QIAO Jinli, MENG Qiujie, LIU Jianqin, JIN Jianxing   +3 more
doaj   +1 more source

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

FEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson, Tomáš Gedeon, Mauricio Garcia Benitez, Campbell Putnam, William R. Harcombe, Radhakrishnan Mahadevan, Ashley E. Beck   +6 more
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Invesitgation of Drilling Parameters on Thrust Force on AZ91 Magnesium Alloy by Genetic Expression Programming

Düzce Üniversitesi Bilim ve Teknoloji Dergisi, 2014
Bu çalışmada AZ91 magnezyum alaşımının farklı parametreler altında işlenmesi ile oluşan kesme kuvvetlerinin deneysel tabanlı teorik bir model ile tahmin edilmesi sunulmuştur.
Kemal ALDAŞ, İskender ÖZKUL, Ahmet TAŞKESEN, Yunus KAYIR   +3 more
doaj   +4 more sources

Prediction the effects of ZnO2 nanoparticles on splitting tensile strength and water absorption of high strength concrete

Materials Research, 2012
In the present paper, two models based on artificial neural networks (ANN) and gene expression programming (GEP) for predicting splitting tensile strength and water absorption of concretes containing ZnO2 nanoparticles at different ages of curing have ...
Ali Nazari, Tohid Azimzadegan
doaj  

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source