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Longevity is heritable and negatively genetically correlated between the sexes in yellow-bellied marmots. [PDF]
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Genetic and evolutionary fitness
American Journal of Medical Genetics, 1978AbstractThe advantages and disadvantages of evolutionary fitness (probability that a single mutant line will not become extinct) and genetic fitness (mean fecundity) are compared. For deterministic processes the two are equivalent, but for stochastic branching processes they may be totally unrelated except that an absolute genetic fitness of unity or ...
Edmond A. Murphy, Robert C. Elston
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Human genetics: An extreme fitness landscape
Current Biology, 2023A new study aims to identify how genetic and physiological adaptations to altitude affect pregnancy, childbirth and neonatal health in one of the most extreme environments on Earth, the Tibetan Plateau.
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Genetics and the Fitness of Hybrids
Annual Review of Genetics, 2001▪ Abstract Over the years, the evolutionary importance of natural hybridization has been a contentious issue. At one extreme is the relatively common view of hybridization as an evolutionarily unimportant process. A less common perspective, but one that has gained support over the past decade, is that of hybridization as a relatively widespread and ...
J M, Burke, M L, Arnold
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Trends in Neurosciences, 2001
High-density oligonucleotide micro-array methods have been used to analyze gene expression in the brain in response to enriched environment training. The results of this study by Rampon et al. indicate that several genes are upregulated under these conditions, such as those with known functions in neuronal structure and synaptic transmission.
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High-density oligonucleotide micro-array methods have been used to analyze gene expression in the brain in response to enriched environment training. The results of this study by Rampon et al. indicate that several genes are upregulated under these conditions, such as those with known functions in neuronal structure and synaptic transmission.
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Genetic Basis of Physical Fitness
Annual Review of Anthropology, 2007Environmental stimuli interact with common genetic variants to determine individual characteristics including physical performance: ∼80% of variation in arm eccentric flexor strength and grip strength may be genetically determined. However, many physical characteristics and physiological processes determine physical performance, and each is regulated ...
Hugh Montgomery, Latif Safari
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Genetic Interactions and Microbial Fitness
2021Abstract Microorganisms can create different genotypes either by mutation or genetic recombination. Transformed or genetically modified bacteria are used in many targets as in the synthesis of large quantities of insulin, in biomining and in bioremediation.
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Inheritance of immunoglobulin E: Genetic model fitting
American Journal of Medical Genetics, 1983AbstractTotal serum immunoglobulin E (IgE) concentration was measured on 316 members of five pedigrees selected through breast cancer probands. Sex‐ and age‐adjusted natural logarithm‐transformed IgE level was not found to differ between individuals with breast cancer or with cancer of any site and other relatives.
Sandra J. Hasstedt +3 more
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Genetic diseases: How the noise fits in
Current Biology, 2023Many disease-causing mutations can have mild or no effects in some people. This incomplete phenotype penetrance phenomenon is still poorly understood, but model animal studies now show that it is stochastic, with the outcome akin to flipping a coin. These findings can affect how genetic diseases are understood and treated.
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