Results 311 to 320 of about 6,603,978 (370)

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

Molecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck, Nele De Meulenaere, Thomas Vanpoucke, Joe Ibrahim, Dieter Peeters, Suresh Krishan Yogeswaran, Wen Wen, Paul Van Schil, Jeroen M. H. Hendriks, Jo Raskin, Jan van Meerbeeck, Guy Van Camp, Ken Op de Beeck   +12 more
wiley   +1 more source

Obliquity in predicted genetic gains with mass and half-sib families selection

, 2004
Alcantara Vilarinho Aloisio
openalex   +1 more source

Strength through diversity: how cancers thrive when clones cooperate

Molecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken, Maartje Witsen, Emile E. Voest, Krijn K. Dijkstra   +3 more
wiley   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

Molecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto, Louise Raunkilde, Jan Lindebjerg, Mads Malik Aagaard, Christina Therkildsen, Jakob Kleif, Lars Henrik Jensen, Torben Frøstrup Hansen, Rikke Fredslund Andersen   +8 more
wiley   +1 more source

Editorial: Precision trait mapping and molecular breeding in high-impact crop plants

Frontiers in Genetics
Dinesh Kumar Saini, Mamta Gupta, Alla Singh, Mehak Sethi, Veena Devi, Reyazul Rouf Mir   +5 more
doaj   +1 more source

Physiological and colorimetric phenotyping in obtaining genetic gains by indirect selection in Capsicum

Rosimara Barboza Bispo, Karina Kazue Nakamura Fukuji, Anderson Yusei Suzuki Fukuji, Cláudia Pombo Sudré, Sabrina Cassaro, Antônio Teixeira do Amaral Júnior, Rosana Rodrigues   +6 more
openalex   +1 more source

Genetic Gain, Advanced Cycle Pedigree Breeding and Correlated Response to Selection under Varying Moisture Conditions in Sunflower

, 2014
Godfree Chigeza
openalex   +1 more source

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From genetic gain to economic gain: simulated growth and financial performance of genetically improved Pinus sylvestris and Pinus pinaster planted stands in France, Finland and Sweden

, 2021
The translation of genetic gains into economic gains is important for evaluating the impact of using genetically improved forest reproductive material (FRM) in the forest sector.
Hernán Serrano-León, A. Ahtikoski, J. Sonesson, B. Fady, M. Lindner, C. Meredieu, A. Raffin, S. Perret, T. Pérot, C. Orazio   +9 more
semanticscholar   +1 more source

A practical guide to genetic gain

Advances in Agronomy, 2019
J. Rutkoski
semanticscholar   +2 more sources