Results 61 to 70 of about 1,295,297 (304)
Inbreeding management and optimization of genetic gain with phenotypic and genomic selection in oil palm (Elaeis guineensis)[W776] [PDF]
, 2020 Oil palm breeding relies on reciprocal recurrent selection between two heterotic groups complementary for bunch number and average bunch weight. Given the long generation interval and the limited selection intensity imposed by the progeny tests currently
Cros, David +2 more
core
Expected Genetic Contributions and Their Impact on Gene Flow and Genetic Gain [PDF]
Genetics, 1999 Abstract Long-term genetic contributions (ri) measure lasting gene flow from an individual i. By accounting for linkage disequilibrium generated by selection both within and between breeding groups (categories), assuming the infinitesimal model, a general formula was derived for the expected contribution of ancestor i in category q (μi(q)
Woolliams, J.A. +2 more
openaire +5 more sources
Evolutionary computing to assemble standing genetic diversity and achieve long-term genetic gain
The Plant Genome, 2023 ABSTRACTLoss of genetic diversity in elite crop breeding pools can severely limit long-term genetic gains, and limit ability to make gains in new traits, like heat tolerance, that are becoming important as the climate changes. Here we investigate and propose potential breeding program applications of optimal haplotype selection (OHS), a selection ...
Kira Villiers +5 more
openaire +3 more sources
Pediatric Blood &Cancer, EarlyView.ABSTRACT Arteriovenous malformations (AVMs) are rare, high‐flow, vascular anomalies that can occur either sporadically or as part of a genetic syndrome. AVMs can progress with serious morbidity and even mortality if left unchecked. Sirolimus is an mTOR inhibitor that is effective in low‐flow vascular malformations; however, its role in AVMs is unclear.
Will Swansson +3 more
wiley +1 more source
Diallel crossing in Pinus cembra : IV. Age trends in genetic parameters and genetic gain for growth and branching traits [PDF]
Annals of Forest Research, 2008 This paper reports results from a complete 10 x 10 diallel carried out in a natural population of Swiss stone pine (Pinus cembra L.) from the southern Carpathian Mountains.
Ioan Blada, Flaviu Popescu
doaj
Animal, 2011 Alternative Norwegian sheep breeding schemes were evaluated by stochastic simulation of a breeding population with about 120 000 ewes, considering the gain for an aggregate genotype including nine traits and also the rate of inbreeding. The schemes were:
L.S. Eikje +3 more
doaj +1 more source
Hyperfunctional complement C3 promotes C5-dependent atypical hemolytic uremic syndrome in mice [PDF]
, 2019 Atypical hemolytic uremic syndrome (aHUS) is frequently associated in humans with loss-of-function mutations in complement-regulating proteins or gain-of-function mutations in complement-activating proteins.
Atkinson, John P +11 more
core +3 more sources
Gain-of-functionHCN2variants in genetic epilepsy [PDF]
Human Mutation, 2017 Genetic generalized epilepsy (GGE) is a common epilepsy syndrome that encompasses seizure disorders characterized by spike-and-wave discharges (SWDs). Pacemaker hyperpolarization-activated cyclic nucleotide-gated channels (HCN) are considered integral to SWD genesis, making them an ideal gene candidate for GGE. We identified HCN2 missense variants from
Li M. +19 more
openaire +4 more sources
Pediatric Blood &Cancer, EarlyView.ABSTRACT Objective To evaluate the diagnostic yield and utility of universal paired tumor–normal multigene panel sequencing in newly diagnosed pediatric solid and central nervous system (CNS) tumor patients and to compare the detection of germline pathogenic/likely pathogenic variants (PV/LPVs) against established clinical referral criteria for cancer ...
Natalie Waligorski +9 more
wiley +1 more source
G3: Genes, Genomes, Genetics, 2017 The long-term performance of different selection strategies was evaluated via simulation using the example of a local cattle breed, German Angler cattle.
Yu Wang +4 more
doaj +1 more source