Results 71 to 80 of about 585,798 (302)

Emapalumab for Immune Effector Cell‐Associated Hemophagocytic Lymphohistiocytosis‐Like Syndrome Following CD19‐Directed CAR‐T in Two Patients With B‐ALL: Clinical and Biomarker Correlates

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Immune effector cell‐associated hemophagocytic lymphohistiocytosis‐like syndrome (IEC‐HS) is a life‐threatening hyperinflammatory toxicity distinct from cytokine release syndrome (CRS) and neurotoxicity following chimeric antigen receptor T‐cell (CAR‐T) therapy. In a single‐institution retrospective cohort of pediatric and young adult patients
Thomas J. Galletta   +6 more
wiley   +1 more source

Integrating genomic selection into dairy cattle breeding programmes: a review

open access: yesAnimal, 2013
Extensive genetic progress has been achieved in dairy cattle populations on many traits of economic importance because of efficient breeding programmes.
A. Bouquet, J. Juga
doaj   +1 more source

In situ assessment of Jatropha curcas germplasm under tropical dry forest conditions in Manabí-Ecuador

open access: yesRevista Facultad Nacional de Agronomía Medellín, 2020
Jatropha germplasm accessions need an assessment of their traits to evaluate the nature and magnitude of the genetic variability among accessions. The objective of this research was to evaluate the phenotypic behavior of 130 Jatropha curcas L. (Jatropha)
Álvaro Cañadas-López   +2 more
doaj   +1 more source

Phenotypic assessment of genetic gain from selection for improved drought tolerance in semi-tropical maize populations

open access: yes, 2023
Most maize production across the globe is rain-fed, and production is set to be negatively impacted as duration and occurrence of droughts increases due to climate change.
Trachsel, S.   +5 more
core   +1 more source

The Role of Hematopoietic Cell Transplantation in Ataxia‐Telangiectasia

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Ataxia‐telangiectasia (A‐T) is a DNA repair disorder characterized by neurodegeneration, immunodeficiency, and cancer predisposition. Hematopoietic cell transplantation (HCT) is an established therapy in related disorders such as Fanconi anemia (FA) and Nijmegen breakage syndrome (NBS), but its role in A‐T is unclear.
Laila Alkhouli   +3 more
wiley   +1 more source

Assessment of Efficiency of Breeding Methods in Accelerating Genetic Gain in Rice

open access: yesAgronomy
The pedigree, bulk, and single-seed descent-based rapid generation advance methods are commonly practiced breeding methods in rice. But the efficiency of these breeding methods in enhancing genetic gain has not been investigated yet.
Partha S. Biswas   +8 more
doaj   +1 more source

Increased Risk of Sarcomas in Children With Congenital Anomalies: Findings From the Genetic Overlap Between Anomalies and Cancer in Kids (GOBACK) Registry Linkage Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Pediatric sarcomas are a heterogeneous group of tumors that contribute disproportionately to cancer mortality in children. Although congenital anomalies are among the strongest known risk factors for childhood cancer, the risk of specific sarcoma subtypes among affected individuals has not yet been thoroughly evaluated. Procedure We
Russ Wolters   +17 more
wiley   +1 more source

Concurrent enhancement of provitamin A and yield in tropical maize hybrids

open access: yesFrontiers in Plant Science
Maize is a strategic food crop in sub-Saharan Africa, where vitamin A deficiency affects millions. Significant investments have thus focused on developing maize varieties that provide 50% of the daily vitamin A requirement for vulnerable populations ...
Abebe Menkir   +8 more
doaj   +1 more source

Genetic variation and gain in progenies of crambe [PDF]

open access: yesCrop Breeding and Applied Biotechnology, 2016
The objective of this study was to estimate the genetic variability of a Brazilian cultivar of crambe, as well as to estimate the genetic gain, with selection focusing on grain yield in crambe. Eighty two progenies were selected within the FMS Brilhante cultivar in 2009.
Lara-Fioreze, Ana Carolina da Costa   +3 more
openaire   +6 more sources

Response to mass selection when an identified major gene is segregating

open access: yes, 1998
A deterministic model to predict response with mass selection when a major locus is segregating is presented. The model uses a selection index framework in which the weight of the different components included in the index are adjusted to describe the ...
Ricardo Pong-Wong   +4 more
core   +1 more source

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