Results 271 to 280 of about 53,278 (329)

Mental health impacts experienced by caregivers of people with Dravet syndrome: A systematic literature review

Epilepsia, EarlyView.
Graphical abstract for the systematic literature review. Abstract Objective Dravet syndrome (DS) places tremendous burden on caregivers owing to the extent of required assistance and impact on daily living, as well as the risk to the individual with DS of premature mortality from sudden unexpected death in epilepsy and morbidity associated with ...
Adam Strzelczyk, Mary Anne Meskis, Galia Wilson, Bobby Jacob, Christoph Helmstaedter, Jane von Gaudecker, Veronica Hood, Ceri Hughes, Michael Scott Perry   +8 more
wiley   +1 more source

Long‐lasting remodeling of astrocytes in an Scna1+/− mouse model of Dravet syndrome

Epilepsia, EarlyView.
Abstract Objective Dravet syndrome (DS) is a prototypical developmental and epileptic encephalopathy caused by mutations in the SCN1A gene, leading to loss of function of the voltage‐gated sodium channel Naᵥ1.1. The latter causes early onset drug‐resistant seizures and enduring cognitive and behavioral deficits.
Athénaïs Genin, Alicia Janvier, Tristan Moujellil‐Legagneur, Marine Blaquière, Alexis Chaussy, Romane Privé, Fabrice Duprat, Massimo Mantegazza, Etienne Audinat, Nicola Marchi, Noémie Cresto   +10 more
wiley   +1 more source

Open diffusion magnetic resonance imaging and connectivity data for epilepsy and surgery: The IDEAS II release

Epilepsia, EarlyView.
Abstract Objective Epileptic seizures are generated in cerebral networks that propagate ictal and interictal activity. The structure of cerebral networks underpinning epileptic activity can be inferred from diffusion‐weighted magnetic resonance imaging (DWI).
Peter N. Taylor, Gerard Hall, Jonathan Horsley, Yujiang Wang, Sjoerd B. Vos, Gavin P. Winston, Andrew W. McEvoy, Anna Miserocchi, Jane de Tisi, John S. Duncan   +9 more
wiley   +1 more source

Unstable slow oscillations couple with epileptogenic fast‐rhythm bistability in sleep‐related epilepsy: A stereoelectroencephalographic study

Epilepsia, EarlyView.
We examined the functional relationship between large‐scale δ‐band phase synchrony and local epileptogenic β–γ‐band amplitude bistability during NREM sleep. Increased synchrony and strong bistability characterized the epileptogenic zone, with strongest effects during N2 sleep, when seizures most frequently occur.
Gaia Burlando, Chiara Belforte, Felix Siebenhühner, Luca Di Tullio, Lorenzo Chiarella, Vladislav Myrov, Frédéric Zubler, Monica Roascio, Francesco Cardinale, Satu Palva, J. Matias Palva, Laura Tassi, Lino Nobili, Gabriele Arnulfo, Sheng H. Wang   +14 more
wiley   +1 more source

High frequency deep brain stimulation of the hippocampus in a rat model for temporal lobe epilepsy [PDF]

, 2006
Boon, Paul, CLAEYS, P, De Smedt, Tim, Leybaert, Luc, Mabilde, Cyriel, Raedt, Robrecht, Van den broecke, Caroline, Wadman, Wytse, Waterschoot, Liesbeth, Wyckhuys, Tine   +9 more
core   +1 more source

Contralateral language network integration predicts and protects against naming decline after temporal lobe resection

Epilepsia, EarlyView.
Abstract Objective Anterior temporal lobe resection (ATLR) is an effective treatment for drug‐resistant temporal lobe epilepsy (TLE) but carries a substantial risk of language impairment, particularly in naming. Understanding and predicting the impact of ATLR on language functions remains a major clinical challenge.
Karl‐Heinz Nenning, Karin Trimmel, Lisa Bartha‐Doering, Marc Berger, Matthias J. Koepp, Georg Langs, Gregor Kasprian, John S. Duncan, Silvia B. Bonelli   +8 more
wiley   +1 more source

Interictal and seizure‐onset scalp electroencephalographic patterns in malformations of cortical development

Epilepsia, EarlyView.
Abstract Objective Malformations of cortical development (MCDs) are a frequent cause of drug‐resistant epilepsy and a common indication for resective epilepsy surgery. As magnetic resonance imaging (MRI) lacks sensitivity for subtle MCDs, supplemental diagnostic tools are needed.
Lubna Shakhatreh, Liz Edenberg P. Quiles, Zhibin Chen, Ofer M. Gonen, Saba Mohidat, Lyn Millist, Callum Hollis, Andrea Sundram, Piero Perucca, Terence J. O'Brien, Patrick Kwan   +10 more
wiley   +1 more source

Artificial intelligence‐assisted detection of epileptic spasms using electroencephalographic–video analysis

Epilepsia, EarlyView.
Abstract Objective This study was undertaken to develop and validate an artificial intelligence (AI) diagnostic tool using hybrid electroencephalographic (EEG)–video signals for automatic epileptic spasms (ES) detection. Methods This retrospective cohort study with internal cross‐validation and multicenter external validation was conducted from July ...
Lin Wan, Nan Lin, Wen Wang, Zi Liang, Yisu Dong, Haibo He, Jian Chen, Yuying Fan, Tong Liu, Hongjie Wang, Weike Cheng, Guangshuang Lu, Juan Wang, Bo Zhang, Qiang Lu, Guang Yang   +15 more
wiley   +1 more source

Arterial spin labeling performs comparably to 2‐[18F]fluoro‐2‐deoxy‐D‐glucose positron emission tomography for presurgical evaluation in pediatric lesional epilepsy

Epilepsia, EarlyView.
Abstract Objective This study was undertaken to test whether arterial spin labeling (ASL) performs comparably to 2‐[18F]fluoro‐2‐deoxy‐D‐glucose positron emission tomography (FDG‐PET), the mainstay functional imaging technique, in pediatric lesional epilepsy, while avoiding radiotracer exposure and additional sedation.
Antonio Giulio Gennari, Dorottya Cserpan, Raimund Kottke, Niklaus Krayenbühl, Michael Messerli, Martin W. Hüllner, Ruth O'Gorman Tuura, Georgia Ramantani   +7 more
wiley   +1 more source

Women with epilepsy: Evidence‐based counseling across the lifespan

Epilepsia, EarlyView.
Abstract Women with epilepsy (WWE) encounter distinct and evolving challenges across the lifespan that require clinical management extending beyond seizure control alone. Although awareness of sex‐specific aspects of epilepsy has increased, important gaps remain in their integration into routine care.
Barbara Tettenborn, Georgia Ramantani, Dominique Flügel, Verena Gaus, Susanne Schubert‐Bast, Elisabeth Sellitto, Jennifer Bausch, Bettina Schmitz   +7 more
wiley   +1 more source