Results 181 to 190 of about 18,747,118 (311)

THE GENETICS OF GROUPS, FOR GROUP READING [PDF]

BioScience, 2005
openaire   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Scaling up orphan crop research: genebank genetics highlight geographic structure in cultivated cowpea from 10 617 global accessions. [PDF]

Plant J
Pearson S, Hathorn A, Sun S, Cruickshank A, Shatte T, Munisse P, Wairimu MM, Conner J, Koltunow A, Vielle-Calzada JP, Ozias-Akins P, Ishii T, Dell'Acqua M, Norton S, Tao Y, Jordan D, Mace E.   +16 more
europepmc   +1 more source

Genetic Evaluation of Cardiomyopathy-A Heart Failure Society of America Practice Guideline.

Journal of Cardiac Failure, 2018
R. Hershberger, M. Givertz, Carolyn Y. Ho, D. Judge, P. Kantor, K. McBride, A. Morales, Matthew R. G. Taylor, M. Vatta, S. Ware   +9 more
semanticscholar   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Commentary: With Regards to the WISDOM trial. [PDF]

BJC Rep
Narod SA.
europepmc   +1 more source

Utilization of Genetic Counseling after Direct-to-Consumer Genetic Testing: Findings from the Impact of Personal Genomics (PGen) Study

Journal of Genetic Counseling, 2017
D. Koeller, W. Uhlmann, D. A. Carere, R. Green, J. Roberts, for the Grips Group   +5 more
semanticscholar   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Elective single embryo transfer in in vitro fertilization cycles with or without preimplantation genetic testing using next-generation sequencing: A randomized clinical trial. [PDF]

Clinics (Sao Paulo)
Peregrino PFM, Nissel CAZ, Florido P, Nakano MS, Messina ML, Soares Júnior JM, Baracat EC, Monteleone PAA.   +7 more
europepmc   +1 more source

A common genetic variation in the 3'-untranslated region of the prothrombin gene is associated with elevated plasma prothrombin levels and an increase in venous thrombosis.

Blood, 1996
S. Poort, F. Rosendaal, P. Reitsma, RM Bertina   +3 more
semanticscholar   +1 more source