Results 201 to 210 of about 18,747,118 (311)

Assessing mung bean genetic diversity with Start Codon Targeted (SCoT) markers: a step towards climate-tolerant varieties for global food security. [PDF]

BMC Plant Biol
Altaf MT.
europepmc   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Genetic Variation in the Main Cultivar Collection of <i>Castanea henryi</i> Revealed by Genome Resequencing. [PDF]

Curr Issues Mol Biol
Wang Y, Yuan X, Yang J, Jiang X, Chen S, Chen H, Li Y.   +6 more
europepmc   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

A topological map of the genetic components of grapevine-Admixture meets SOMmelier machine learning. [PDF]

PLoS Comput Biol
Baloyan A, Konecny T, Hovhannisyan E, Zadirako N, Nikoghosyan M, Binder H.   +5 more
europepmc   +1 more source

Blood groups and human genetics.

The Turkish journal of pediatrics, 1966
openaire   +2 more sources

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

P100: Predictive accuracy of liquid biopsy for comprehensive genomic profiling of solid tumors*

Genetics in Medicine Open
Nathan Hassel, Suyeon Ryu, Jamie Phan, Michael Sweredoski, Negar Ghahramani, Mike Moradian, Ruan Ramjit   +6 more
doaj   +1 more source

Genetic structure analysis of a Northwest Chinese population using a self-developed DIP system and machine learning for forensic ancestry inference. [PDF]

BMC Genomics
Cai M, Shen R, Shi X, Wu Y, Luo L, Liang Q, Zhu B.   +6 more
europepmc   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source