Results 101 to 110 of about 5,062,045 (260)
Genetic control of gibberellin metabolism and signalling in crop improvement
, 2016 Many developmental processes regulated by gibberellin (GA) impact on crop yield and quality, and genetic variants affected in GA biosynthesis or signalling have been widely exploited in agriculture.
Phillips, A. L., Andrew L. Phillips
core +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Carp genetic resources for aquaculture in Asia [PDF]
There are over 1 300 species of cyprinids in Asia, which form an important part of the worldÆs aquatic biodiversity. Aquaculture and capture fisheries involving cyprinids are a vital part of the livelihoods of many millions of people in this region. The
Gupta, M.V. +2 more
core
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Hyderabad City Improvement Proposal
, 2007 full view, showing City Improvement Board proposal for development of roads, railway line, residential areas, public buildings, parks, graveyards, city wall and municipal boundary based on M.
Fayyazuddin, Muhammad +1 more
core
Nature CommunicationsDrought and heat are major abiotic stresses frequently coinciding to threaten rice production. Despite hundreds of stress-related genes being identified, only a few have been confirmed to confer resistance to multiple stresses in crops.
Yu Chang +8 more
doaj +1 more source
Discerning protein pools by selective staining with self‐labeling tags
FEBS Letters, EarlyView.Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley +1 more source
Maximizing Genetic Response in Breeding Schemes of Dairy Cattle with Constraints on Variance of Response [PDF]
, 1994 Predicted genetic progress in dairy cattle breeding schemes was maximized with the variances of selection responses constrained, i.e., restricted effective population sizes. This restriction would also lead to schemes with acceptable rates of inbreeding (
Woolliams, John, Meuwissen, T.H.E.
core
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source