Results 131 to 140 of about 5,357,131 (305)

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Coordinated regulation of nitrogen transport and assimilation drives high nitrogen use efficiency in sugarcane

Frontiers in Plant Science
Improving nitrogen use efficiency (NUE) is essential for sustainable sugarcane production. Breeding high-NUE varieties enables high yields under low nitrogen (N) input, and identifying NUE-related genes is a critical step for molecular breeding.
Cui-Xian Qin, Zhong-Liang Chen, Ao-Mei Li, Miao Wang, Jiao-Yun Chen, You-Qiang Pan, Fen Liao, Dong-Liang Huang   +7 more
doaj   +1 more source

Genetic improvement and its effect on the genetic diversity of habanero chili (capsicum chinense jacq.) [PDF]

Genetic improvement and its effect on the genetic diversity of habanero chili (Capsicum chinense Jacq.
Castillo-Aguilar, Crescencio C., Chiquini-Medina Ramón A., Chiquini-Medina Ricardo A.   +2 more
core   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Genome-wide reprogramming of sRNA and lncRNA in the epigenetic regulation following interspecific hybridization in the Brassica species

Molecular Horticulture
Interspecific hybridization has a significant impact on the inheritance of non-coding RNAs (ncRNAs), resulting in alterations in gene expression and phenotypic variation.
Chengtao Quan, Ling Wang, Hangpan Wei, Yilin Ma, Yunqin Wang, Guoting Cheng, Chaozhi Ma, Cheng Dai   +7 more
doaj   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Robustly enhancing crop genomic prediction accuracy through ensemble learning and iterative optimization

Nature Communications
With climate change and global population growth, accelerating the breeding of superior crop varieties is essential for food security. Genomic prediction, which uses genome-wide genetic markers to predict crop traits, plays an important role in ...
Zhou Yao, Liguang Wang, Li Zhu, Xinle Li, Qiqi Wu, Fan Wu, Guoshuai Wang, Wenyu Yang, Yingjie Xiao, Jianxiao Liu   +9 more
doaj   +1 more source

The dilemma of food genetics and improvement

Open Life Sciences
Abstract The advancement of genetic techniques in food production offers significant potential for improving crop quality, yield, and sustainability. However, these innovations present a complex set of dilemmas concerning nutritional quality, food authenticity, socioeconomic implications, regulatory challenges, and human health.
openaire   +2 more sources

Hyderabad City Improvement Proposal

, 2007
full view, showing City Improvement Board proposal for development of roads, railway line, residential areas, public buildings, parks, graveyards, city wall and municipal boundary based on M.
Fayyazuddin, Muhammad, City Improvement Board   +1 more
core  

WorldFish Carp Genetic Improvement Program (CGIP)

, 2022
WorldFish Genetics Workshop 2022 - ppt presentation on the WorldFish Carp Genetic Improvement Program (CGIP)
Hamilton, Matthew
core