Results 131 to 140 of about 625,256 (313)

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

Live animal measurements, carcass composition and plasma hormone and metabolite concentrations in male progeny of sires differing in genetic merit for beef production

, 2009
peer-reviewedIn genetic improvement programmes for beef cattle, the effect of selecting for a given trait or index on other economically important traits, or their predictors, must be quantified to ensure no deleterious consequential effects go unnoticed.
Evans, R. D., Kenny, David A., McGee, Mark, Clarke, Anne Marie, Drennan, Michael J, Berry, Donagh   +5 more
core   +1 more source

Genome-wide reprogramming of sRNA and lncRNA in the epigenetic regulation following interspecific hybridization in the Brassica species

Molecular Horticulture
Interspecific hybridization has a significant impact on the inheritance of non-coding RNAs (ncRNAs), resulting in alterations in gene expression and phenotypic variation.
Chengtao Quan, Ling Wang, Hangpan Wei, Yilin Ma, Yunqin Wang, Guoting Cheng, Chaozhi Ma, Cheng Dai   +7 more
doaj   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

FEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Genetic parameters for social effects on survival in cannibalistic layers: Combining survival analysis and a linear animal model

, 2010
Background Mortality due to cannibalism in laying hens is a difficult trait to improve genetically, because censoring is high (animals still alive at the end of the testing period) and it may depend on both the individual itself and the behaviour of its ...
Veerkamp Roel F, Veerkamp, Roel F., Ducrocq, V.P., Ducrocq, Vincent, Bijma, Piter, Bijma Piter, Ducro, B.J., Esther D Ellen, Ellen, Esther D., Bijma, P., Ellen Esther D, Ellen, E.D., Veerkamp, Roel F, Roel F Veerkamp, Ducro, Bart J., Veerkamp, R.F., Vincent Ducrocq, Ducro Bart J, Bart J Ducro, Ducrocq Vincent, Ducro, Bart J, Piter Bijma   +21 more
core   +1 more source

Effect of Altitude on the Agronomic Performance of Four Improved Maize Varieties Under Dissemination in Côte d’Ivoire

International Journal of Agronomy
Maize is a staple crop for millions, yet its production in Côte d’Ivoire remains below potential despite advances in improved varieties. Environmental conditions, including altitude, potentially influence maize performance, but data on altitude’s effect ...
Lassana Tioté, Yaya Nadiala Coulibaly, Yao Raymond Koffi   +2 more
doaj   +1 more source

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

FEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson, Tomáš Gedeon, Mauricio Garcia Benitez, Campbell Putnam, William R. Harcombe, Radhakrishnan Mahadevan, Ashley E. Beck   +6 more
wiley   +1 more source

Perspectives from Agriculture: Advances in livestock breeding-Implications of aquaculture genetics [PDF]

In this paper we present livestock breeding developments that could be taken into consideration in the genetic improvement of farmed aquaculture species, especially in freshwater fish.
Ponzoni, R.W., Nguyen, N.H., WorldFish Center   +2 more
core  

Coordinated regulation of nitrogen transport and assimilation drives high nitrogen use efficiency in sugarcane

Frontiers in Plant Science
Improving nitrogen use efficiency (NUE) is essential for sustainable sugarcane production. Breeding high-NUE varieties enables high yields under low nitrogen (N) input, and identifying NUE-related genes is a critical step for molecular breeding.
Cui-Xian Qin, Zhong-Liang Chen, Ao-Mei Li, Miao Wang, Jiao-Yun Chen, You-Qiang Pan, Fen Liao, Dong-Liang Huang   +7 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source