Results 191 to 200 of about 7,966,330 (339)

Genetic improvement of a synthetic microbiota: a step further? [PDF]

Front Microbiol
Martínez-Porchas M, Medina-Félix D, Vargas-Albores F, Garibay-Valdez E, Méndez-Martínez Y, Martínez-Córdova LR, Ortiz-Estrada AM.   +6 more
europepmc   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Plant oil biosynthesis and genetic improvement: progress, challenges, and opportunities. [PDF]

Plant Physiol
Tong C, Ding Y, Cheng X, Liu L, Liu X, Zhang Y, Xia Y, Li M, Liu S.   +8 more
europepmc   +1 more source

Proceedings of a workshop on the development of a genetic improvement program for African catfish Clarias gariepinus [PDF]

This proceedings include papers present at the workshop held from 5 to 9th Nov 2007 in Accra, Ghana. The areas cover 1)the present state of the catfish industry in Africa 2)Catfish reproductive management and grow out 3)Catfish nutrition and feeds 4)The ...
Nguyen, N.H. (eds.), Ponzoni, R.W.
core  

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

Molecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero, Alejandro Belmonte‐Fernández, Mónica González‐Moreno, Laura Rodríguez‐Cordero, Begoña Pérez‐Valderrama, Joaquín Herrero‐Ruíz, Francisco Romero, Carmen Sáez, Miguel Á. Japón   +8 more
wiley   +1 more source

Assessing the Reliability of Automatic Milking Systems Data to Support Genetic Improvement in Dairy Cattle. [PDF]

Animals (Basel)
Ponzo E, Moretti R, Masia F, Vrieze E, Sacchi P, Chessa S.   +5 more
europepmc   +1 more source

Mango genetic improvement [PDF]

, 1993
Bally, I. S. E.
core   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Analysis of the Hip Status of Golden Retrievers in Brazil-A Study of Health and Genetic Improvement. [PDF]

Vet Sci
Pinto Coelho Ribeiro Jardim L, Michelsen de Andrade F, Tyska DU, Cobuci JA.   +3 more
europepmc   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source