Results 181 to 190 of about 625,256 (313)

The Contribution of Genetic Resources and Diversity to Wheat Productivity: A Case from the Punjab of Pakistan

This study makes use of data on wheat production in the Punjab of Pakistan from 1979 to 1985 to 1) examine patterns of varietal diversity in farmers' fields both at the regional and district levels and 2) identify how and in what ways genetic resources ...
Hartell, Jason G., Heisey, Paul W., Senauer, Benjamin, Smale, Melinda   +3 more
core  

Telomere-to-telomere genome assembly and a mutant library empower functional genomics and genetic improvement in Cucurbita moschata. [PDF]

Plant Commun
Li J, Chen Z, Li K, Tan J, Sun J, Deng XW, Park Y, He H, Deng Y, Zhang X.   +9 more
europepmc   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Plant oil biosynthesis and genetic improvement: progress, challenges, and opportunities. [PDF]

Plant Physiol
Tong C, Ding Y, Cheng X, Liu L, Liu X, Zhang Y, Xia Y, Li M, Liu S.   +8 more
europepmc   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

A multidimensional core set development of sesame germplasm leveraging agro-morphological traits diversity for genetic improvement and climate resilience. [PDF]

Sci Rep
Yadav R, Vishwakarma H, Satpathy S, Mahalingam A, Rangan P, Kumar A, Ali S, Sharma K, Kumari K, Arya DK, Rialch I, Kumhar SR, Gohil V, Bisen R, Pandey R, Rai V, Tiwari K, Singh AK, Angadi UB, Vasimalla CC, Senthilraja G, Sharma P, Kumar P, Gupta KN, Ranebennur H, Singh K, Langyan S, Rana VS, Shakil NA, Sharma S, Singh A, Choudhary R, Pradheep K, Gomashe SS, Ramachandran S, Singh M, Aravind J, Jalli R, Kumar A, Singh K, Singh GP, Kalia S, Rathore A.   +42 more
europepmc   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Assessing the Reliability of Automatic Milking Systems Data to Support Genetic Improvement in Dairy Cattle. [PDF]

Animals (Basel)
Ponzo E, Moretti R, Masia F, Vrieze E, Sacchi P, Chessa S.   +5 more
europepmc   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source

Analysis of the Hip Status of Golden Retrievers in Brazil-A Study of Health and Genetic Improvement. [PDF]

Vet Sci
Pinto Coelho Ribeiro Jardim L, Michelsen de Andrade F, Tyska DU, Cobuci JA.   +3 more
europepmc   +1 more source