Results 121 to 130 of about 283,128 (311)

Tight genetic linkage of genes causing hybrid necrosis and pollinator isolation between young species. [PDF]

Nat Plants, 2023
Li C, Binaghi M, Pichon V, Cannarozzi G, Brandão de Freitas L, Hanemian M, Kuhlemeier C.   +6 more
europepmc   +1 more source

MET and NF2 alterations confer primary and early resistance to first‐line alectinib treatment in ALK‐positive non‐small‐cell lung cancer

Molecular Oncology, EarlyView.
Alectinib resistance in ALK+ NSCLC depends on treatment sequence and EML4‐ALK variants. Variant 1 exhibited off‐target resistance after first‐line treatment, while variant 3 and later lines favored on‐target mutations. Early resistance involved off‐target alterations, like MET and NF2, while on‐target mutations emerged with prolonged therapy.
Jie Hu, Ning Ding, Xiaobo Xu, Yedan Chen, Yong Zhang, Jingwen Liu, Jiebai Zhou, Hairong Bao, Donghui Zhang, Yijun Song, Yang Shao, Yuanlin Song   +11 more
wiley   +1 more source

Construction of a high-density genetic linkage map and QTL mapping for bioenergy-related traits in sweet sorghum [Sorghum bicolor (L.) Moench]. [PDF]

Front Plant Sci, 2023
Guden B, Yol E, Erdurmus C, Lucas SJ, Uzun B.   +4 more
europepmc   +1 more source

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

Molecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani, Gilgi Friedlander, Gili Perry, Nora Balint‐Lahat, Shlomit Gilad, Dana Morzaev‐Sulzbach, Anjana Shenoy, Noa Bossel Ben‐Moshe, Anya Pavlovsky, Rinat Bernstein‐Molho, Eytan Domany, Iris Barshack, Tamar Geiger, Bella Kaufman, Einav Nili Gal‐Yam   +14 more
wiley   +1 more source

Construction of a high density genetic linkage map to define the locus conferring seedlessness from Mukaku Kishu mandarin. [PDF]

Front Plant Sci, 2023
Kumar K, Yu Q, Bhatia D, Honsho C, Gmitter FG.   +4 more
europepmc   +1 more source

Genetical studies on rice plant. : The order and distance of some genes belong to P1-linkage group.

, 1952
Seijin NAGAO, Man-emon Takahashi
openalex   +2 more sources

X-LINKAGE OF A HUMAN GENETIC LOCUS THAT CORRECTS THE DNA SYNTHESIS LESION IN tsC1AGOH MOUSE CELLS [PDF]

, 1979
Richard E. Giles, Frank H. Ruddle
openalex   +1 more source

Ubiquitination of transcription factors in cancer: unveiling therapeutic potential

Molecular Oncology, EarlyView.
In cancer, dysregulated ubiquitination of transcription factors contributes to the uncontrolled growth and survival characteristics of tumors. Tumor suppressors are degraded by aberrant ubiquitination, or oncogenic transcription factors gain stability through ubiquitination, thereby promoting tumorigenesis.
Dongha Kim, Hye Jin Nam, Sung Hee Baek
wiley   +1 more source

High-density genetic linkage mapping reveals low stability of QTLs across environments for economic traits in Eucalyptus. [PDF]

Front Plant Sci, 2022
Zhu X, Weng Q, Bush D, Zhou C, Zhao H, Wang P, Li F.   +6 more
europepmc   +1 more source

Evolutionary conserved close linkage of the c-fes/fps proto-oncogene and genetic sequences encoding a receptor-like protein. [PDF]

, 1986
Anton Roebroek, Jack A. Schalken, J.A.M. Leunissen, C. Onnekink, Henri P.J. Bloemers, W J Van de Ven   +5 more
openalex   +1 more source