Results 131 to 140 of about 3,634,544 (343)
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Background High-resolution genetic linkage map is critical for QTL mapping, genome sequence assembly and marker-assisted selection in aquaculture species.
Jitao Li +5 more
doaj +1 more source
Co-occurring risk factors for alcohol dependence and habitual smoking. [PDF]
Smoking and alcohol dependence frequently occur together, and both behaviors are determined in part by genetic influences. The Collaborative Study on the Genetics of Alcoholism (COGA), which is investigating the genetic factors contributing to alcohol ...
Bierut, LJ +3 more
core
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
The genomic Make-Up of a Hybrid Species - Analysis of the Invasive Cottus Lineage (Pisces, Teleostei) in the River Rhine system [PDF]
In the past years a new invasive lineage of sculpins (Cottus species complex) has been studied that is currently expanding in the Lower River Rhine. Molecular analysis showed that this lineage has originated through hybridization of Cottus perifretum ...
Stemshorn, Kathryn
core
We propose a new method for hierarchical clustering based on the optimisation of a cost function over trees of limited depth, and we derive a message--passing method that allows to solve it efficiently.
A Braunstein +7 more
core +1 more source
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Genetic Maps/1984, volume 3: A Compilation of Linkage and Restriction Maps of Genetically Studied Organisms. Edited by Stephen J. O'Brien. New York: Cold Spring Harbor Laboratory. 1984. 583 pages (approx.). $28 U.S.A. $33.60 elsewhere. ISBN 0 87969 1719. [PDF]
Eric Reeve
openalex +1 more source
De novo construction of polyploid linkage maps using discrete graphical models
Linkage maps are used to identify the location of genes responsible for traits and diseases. New sequencing techniques have created opportunities to substantially increase the density of genetic markers.
Behrouzi, Pariya, Wit, Ernst C.
core +1 more source

