Results 291 to 300 of about 547,025 (332)

Development and validation of systems for genetic manipulation of the Old World tick-borne relapsing fever spirochete, Borrelia duttonii. [PDF]

open access: yesPLoS Negl Trop Dis
Jackson-Litteken CD   +8 more
europepmc   +1 more source

Genetic manipulation of radiosensitivity

International Journal of Radiation Oncology*Biology*Physics, 2001
Human tumor cell lines in culture show a wide range of radiosensitivity. Values for SF2 (surviving fraction at 2 Gy) typically range from 0.2 to 0.9 (data from our own laboratory). Radiotherapy employing 30–35 fractions of 2 Gy would therefore result in levels of cell kill that would mean certain failure for the most resistant tumors and certain cure ...
A C, Begg, C, Vens
openaire   +2 more sources

Genetic manipulation of schistosomes

International Journal for Parasitology, 2007
In contrast to the situations with model organisms and parasitic protozoa, progress with gene manipulation with schistosomes has been delayed by impediments that include our inability to maintain the life cycle in vitro, absence of immortalized cell lines, large genome sizes, unavailability of drug resistance markers and other difficulties. However, in
Paul J, Brindley, Edward J, Pearce
openaire   +2 more sources

Genetic Manipulations in Dermatophytes

Mycopathologia, 2016
Dermatophytes are a group of closely related fungi that nourish on keratinized materials for their survival. They infect stratum corneum, nails, and hair of human and animals, accounting the largest portion of fungi causing superficial mycoses. Huge populations are suffering from dermatophytoses, though the biology of these fungi is largely unknown yet.
Mohamed Mahdi Alshahni, Tsuyoshi Yamada
openaire   +2 more sources

Genetic manipulation system in propionibacteria

Journal of Bioscience and Bioengineering, 2002
Members of the genus Propionibacterium are widely used in the production of vitamin B12, tetrapyrrole compounds, and propionic acid as well as in probiotic and cheese industries. Shuttle vectors were developed in propionibacteria using replicons from endogenous plasmids in Propionibacterium and Escherichia coli and an appropriate selection marker.
Pornpimon, Kiatpapan   +1 more
openaire   +2 more sources

Genetic Manipulation of Kinetoplastida

Parasitology Today, 1999
During the 1980s, many kinetoplastid genes were cloned and their function inferred from homology with genes from other organisms, location of the corresponding proteins or expression in heterologous systems. Up until 1990, before the availability of DNA transfection methodology, we could not analyze the function of kinetoplastid genes within the ...
openaire   +2 more sources

Genetic Manipulations with Elms

2000
Genetic manipulation by transformation is a powerful alternative to conventional elm breeding programs, allowing the rapid introduction of small numbers of desirable genes into elite genotypes without disrupting their better genetic features. To achieve this, systems for the micropropagation and regeneration of English elm (Ulmus procera), American elm
Gartland, K.   +6 more
openaire   +2 more sources

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