Results 301 to 310 of about 547,025 (332)
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Genetic Manipulation of Noradrenergic Neurons
The Journal of Pharmacology and Experimental Therapeutics, 2002The neurotransmitter norepinephrine has been the focus of intense investigation for nearly a century. With advances in technology come novel approaches for testing hypotheses about the physiological roles of norepinephrine and the genes involved in norepinephrine (NE) biosynthesis, metabolism, and noradrenergic signaling.
Robert P, Carson, David, Robertson
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1984
In the past ten years several advances in biotechnology have revolutionized the way fundamental biological problems are approached. I will discuss three of these relatively recently developed disciplines in biotechnology—recombinant DNA, microchemical instrumentation, and monoclonal antibodies—and I will point out the striking synergies that arise from
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In the past ten years several advances in biotechnology have revolutionized the way fundamental biological problems are approached. I will discuss three of these relatively recently developed disciplines in biotechnology—recombinant DNA, microchemical instrumentation, and monoclonal antibodies—and I will point out the striking synergies that arise from
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Genetic manipulation of Bacillus amyloliquefaciens
Journal of Biotechnology, 1991Application of modern gene technology to strain improvement of the industrially important bacterium Bacillus amyloliquefaciens is reported. Several different plasmid constructions carrying the alpha-amylase gene (amyE) from B. amyloliquefaciens were amplified in this species either extrachromosomally or intrachromosomally.
J, Vehmaanperä +2 more
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Genetic Manipulation Techniques
2014In the past two decades we have seen a very important advance in the research of the biology of Entamoeba histolytica. This dramatic progress has been mostly the result of (1) the introduction of a transfection system to express exogenous genes and to up- and downregulate the expression of selected genes, (2) the completion of the parasite’s genome ...
David Mirelman, Rivka Bracha
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Genetic Manipulation of Mycoplasma pneumoniae
2023Mycoplasma pneumoniae is a small cell wall-lacking bacterium that is a common cause of bronchitis and pneumonia in humans. In addition to its clinical importance, M. pneumoniae has recently been considered a promising model organism for synthetic biology because of its small genome size and unique cell structure. At one cell pole, M.
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Techniques for Genetic Manipulation
In the last few decades, molecular techniques and genetic modification have been used in genotype and phenotype studies of S. suis. Genomic modification of S. suis requires DNA acquisition and its stable insertion into the chromosome by allelic exchange. In this chapter, we described two techniques for the preparation of genomic constructs (cloning andCarla, García López +6 more
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Genetic Manipulation of Staphylococci
2013The ability to genetically manipulate bacteria is essential to understanding gene/protein function in these organisms. While basic cloning has become routine in molecular biology, many still view the ability to make directed mutations as a daunting or intimidating task.
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Mitochondrial Genetic Manipulation
2015Mitochondria are key players in cellular metabolism and energy production. They have their own genetic system. The mitochondrial genome is small and contains a limited number of genes, but its expression is complex and essential for survival. Organelle DNA mutations or rearrangements cause incurable neurodegenerative diseases in humans or cytoplasmic ...
Daria Mileshina +4 more
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Antibiotics: opportunities for genetic manipulation
Philosophical Transactions of the Royal Society of London. B, Biological Sciences, 1989New antibiotics can still be discovered by the development of novel screening procedures. Notable successes over the last few years include the monobactams, β- lactamase inhibitors (clavulanic acid) and new glycopeptides in the antibacterial held; antiparasitic agents such as avermectins; and herbicidal antibiotics like bialaphos.
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2017
The importance of the molecular biology of S. cerevisiae is closely related species is well documented. This yeast was the first microorganism to be domesticated for the production of fermented food and beverages and to be described as a living biochemical agent for biological transformations. In 1996, the complete genome of S.
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The importance of the molecular biology of S. cerevisiae is closely related species is well documented. This yeast was the first microorganism to be domesticated for the production of fermented food and beverages and to be described as a living biochemical agent for biological transformations. In 1996, the complete genome of S.
openaire +1 more source