Results 71 to 80 of about 547,025 (332)
Cas9+ conditionally-immortalized macrophages as a tool for bacterial pathogenesis and beyond. [PDF]
, 2019 Macrophages play critical roles in immunity, development, tissue repair, and cancer, but studies of their function have been hampered by poorly-differentiated tumor cell lines and genetically-intractable primary cells.
Barton, Gregory M +7 more
core
Mechanisms of parasite‐mediated disruption of brain vessels
FEBS Letters, EarlyView.Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source
The cell adhesion molecule Fasciclin2 regulates brush border length and organization in Drosophila renal tubules [PDF]
, 2016 Multicellular organisms rely on cell adhesion molecules to coordinate cell–cell interactions, and to provide navigational cues during tissue formation.
Davies, Shireen-Anne +7 more
core +2 more sources
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
Methods for the genetic manipulation of marine bacteria
Electronic Journal of Biotechnology, 2018 Genetic manipulation of bacteria is a procedure necessary to obtain new strains that express peculiar and defined genetic determinants or to introduce genetic variants responsible for phenotypic modifications. This procedure can be applied to explore the
Zahraa Zeaiter +3 more
doaj +1 more source
Regeneration of begonia plantlets by direct organogenesis [PDF]
, 2009 The economic importance of ornamentals worldwide suggests a bright future for ornamental breeding. Rapid progress in plant molecular biology has great potentials to contribute to the breeding of novel ornamental plants utilizing recombinant DNA ...
Curuk, P. +6 more
core
New Clox Systems for rapid and efficient gene disruption in Candida albicans [PDF]
, 2014 Acknowledgements: We are grateful to Janet Quinn, Lila Kastora, Joanna Potrykus, Michelle Leach, and others for sharing their experiences with the Clox cassettes.
Ballou, Elizabeth R +6 more
core +4 more sources
Materials Today, 2005 Over the last 15 years, the use of atomic force microscopy (AFM) has spread from the materials science of hard matter to the fields of biology and biomolecular research. Nowadays, AFM can be used not only as a high-resolution imaging tool for precise cytogenetic studies, but also for the mechanical measurement and manipulation of genetic material. This
Thalhammer, Stefan, Heckl, Wolfgang M.
openaire +1 more source
Molecular Oncology, EarlyView.PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham +21 more
wiley +1 more source
Frontiers in NutritionInvestigating Moringa oleifera (M. oleifera)’ is potential as a livestock feed additive, this review explores its nutritional and phytochemical profiles and its mechanistic roles, specifically focusing on its immunomodulatory and antioxidant properties ...
Raza Mohai Ud Din +9 more
doaj +1 more source