Results 131 to 140 of about 12,859,837 (351)
Molecular Oncology, EarlyView.The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source
Animals, 2019 Maternal breeds for sows have been bred for high prolificacy during recent decades. Although large litters may be beneficial for economic efficiency, pre-weaning mortality is increased.
Katharina Schodl +7 more
doaj +1 more source
Genetic algorithm for the pair distribution function of the electron gas
, 2011 The pair distribution function of the electron gas is calculated using a parameterized generalization of quantum hypernetted chain approximation with the parameters being obtained by optimizing the system energy with a genetic algorithm. The functions so
Carlevaro, C. Manuel +3 more
core +1 more source
Genetic parameters for production, health, fertility and longevity traits in dairy cows.
Animal, 2013 Milk production, fertility, longevity and health records, were extracted from databases of two milk recording organisations in the United Kingdom for the first three lactations of the Holstein-Friesian breed. These included data related to health events (
T. Pritchard +3 more
semanticscholar +1 more source
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
The role of Dark Matter interaction in galaxy clusters
, 2012 We consider a toy model to analyze the consequences of dark matter interaction with a dark energy background on the overall rotation of galaxy clusters and the misalignment between their dark matter and baryon distributions when compared to {\Lambda}CDM ...
Abdalla, Elcio +6 more
core +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Scientific Papers Animal Science and Biotechnologies, 2023 Aim of this study was estimation of two genetic parameters: heritability and repeatability, for five milk production traits. Data used in current paper consisted from phenotypic information from 998 cows with 1897 yield records.
Nicoleta Roşca (Dulgheru) +2 more
doaj
Ciência e Agrotecnologia, 2010 O manejo de plantas em cultivo protegido e a busca de produtos orgânicos pelos consumidores têm sido um desafio para produtores e pesquisadores de hortaliças.
Sarah Ola Moreira +4 more
doaj +1 more source
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source