Results 191 to 200 of about 12,859,837 (351)

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

Genetic Parameters of Egg Quality Traits and Albumen Density in White Leghorn Chickens. [PDF]

Animals (Basel)
Chen A, Wang H, Zuo D, Li H, Wang H, Ning Z, Ban L, Qu C, Zhao X, Qu L.   +9 more
europepmc   +1 more source

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

FEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies, Garth L. Maker, Ian F. Musgrave, Samantha Lodge   +3 more
wiley   +1 more source

Genetic parameters for alternative resilience phenotypes in Holstein cows. [PDF]

JDS Commun
Guinan FL, Fourdraine RH, Peñagaricano F, Weigel KA.   +3 more
europepmc   +1 more source

Bayesian estimation of genetic parameters.

Japanese Journal of Breeding, 1990
Kenziro SAIO, Takeshi HAYASHI
openaire   +2 more sources

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Genetic parameters for feed efficiency, growth performance, and feeding behaviors traits in Canadian Duroc pigs. [PDF]

J Anim Sci
Do DN, Jafarikia M, Maignel L, Tulpan D, Adewole D, Holl J, Sullivan B, Miar Y.   +7 more
europepmc   +1 more source

Comparison of Bayesian and maximum-likelihood inference of population genetic parameters

Bioinform., 2006
Peter Beerli
semanticscholar   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

Large-scale automated measurement and genetic parameters analysis of early-life myofiber characteristics in broilers. [PDF]

Poult Sci
Yang Y, Wang C, Li G, Yan Y, Wu G, Wen C, Yang N.   +6 more
europepmc   +1 more source