Estimating genetic parameters in natural populations using the "animal model".
L. Kruuk
semanticscholar +1 more source
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid +3 more
wiley +1 more source
Effect of Transformation of Non-Normal Fitness Trait Data on the Estimation of Genetic Parameters in Turkeys. [PDF]
Hartono E +5 more
europepmc +1 more source
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu +5 more
wiley +1 more source
Genetics of gait score in broilers: Genetic parameters of gait score in purebred broiler lines. [PDF]
Kapell DNRG +4 more
europepmc +1 more source
Optimization of Proportional–Integral (PI) and Fractional-Order Proportional–Integral (FOPI) Parameters Using Particle Swarm Optimization/Genetic Algorithm (PSO/GA) in a DC/DC Converter for Improving the Performance of Proton-Exchange Membrane Fuel Cells [PDF]
Yurdagül Benteşen Yakut
openalex +1 more source
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava +3 more
wiley +1 more source
Genetic Parameters, Prediction of Genotypic Values, and Forage Stability in <i>Paspalum nicorae</i> Parodi Ecotypes via REML/BLUP. [PDF]
Silveira DC +9 more
europepmc +1 more source
Genetic parameters for linear type traits in the Rendena dual-purpose breed.
S. Mazza +4 more
semanticscholar +1 more source

