Results 71 to 80 of about 1,975,129 (302)

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Genetic Analysis of a Commercial Egg Laying Line Challenged With Newcastle Disease Virus

open access: yesFrontiers in Genetics, 2018
In low income countries, chickens play a vital role in daily life. They provide a critical source of protein through egg production and meat. Newcastle disease, caused by avian paramyxovirus type 1, has been ranked as the most devastating disease for ...
Kaylee Rowland   +8 more
doaj   +1 more source

Distributions of Triplets in Genetic Sequences [PDF]

open access: yes, 1997
Distributions of triplets in some genetic sequences are examined and found to be well described by a 2-parameter Markov process with a sparse transition matrix.
Boon   +10 more
core   +3 more sources

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

The effects of population size on genetic parameters and mating system of sandalwood in Gunung Sewu, Indonesia

open access: yesIndonesian Journal of Biotechnology, 2015
We combined feld observations with isoenzyme analysis to compare population demographic and its effects on genetic diversity and mating systems, among six populations of sandalwood in Gunung Sewu, Indonesia, during March to August 2015.
Yeni Widyana Nurchahyani   +3 more
doaj   +1 more source

Parameter Selection in Genetic Algorithms

open access: yesJournal of Systemics, Cybernetics and Informatics, 2004
In this study, we provide a new taxonomy of parameters of genetic algorithms (GA), structural and numerical parameters, and analyze the effect of numerical parameters on the performance of GA based simulation optimization applications with experimental design techniques. Appropriate levels of each parameter are proposed for a particular problem domain.
BOYABATLI, Onur, SABUNCUOGLU, Ihsan
openaire   +2 more sources

Estimating quantitative genetic parameters in haplodiploid organisms [PDF]

open access: yesHeredity, 2000
Haplodiploid organisms (diploid females and haploid males) are genetically distinct in that they have asymmetrical genetic segregation, gene dosage compensation in the haploid male, maternal effects, and a general propensity to inbreed. Taking these characteristics into account, we demonstrate how conventional experimental designs and statistics ...
F H, Liu, S M, Smith
openaire   +2 more sources

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Estimates of genetic parameters of wood traits for sawn timber production in Eucalyptus grandis

open access: yesGenetics and Molecular Biology, 2004
In this study, the breeding perspectives of 41 open-pollinated progenies of Eucalyptus grandis were evaluated based on their wood traits. The progenies were distributed in two experiments in a randomized complete block design, with three replicates and ...
Paulo Eduardo Telles dos Santos   +2 more
doaj   +1 more source

Home - About - Disclaimer - Privacy