XChrom is a deep learning framework that integrates genomic sequence and single‐cell context to predict chromatin accessibility. It generalizes to unseen cells and genomic regions, enabling cross‐sample and cross‐species analysis. Applied to COVID‐19 patient data, XChrom reveals key transcriptional regulatory mechanisms and disease‐associated ...
Yuanyuan Miao +5 more
wiley +1 more source
Hydrodynamic Selection of Polymorphic Assembly Pathways in Plant Protein Amyloid Fibrils
Hydrodynamic conditions are revealed to govern polymorphic assembly of soy protein amyloid fibrils. Distinct flow‐induced drafting, kissing, and docking dynamics direct fibril growth into multiple morphologies, linking fluid mechanics with nanoscale assembly and enabling rational design of functional amyloid materials.
Zejian Xu +8 more
wiley +1 more source
Genetic Polymorphisms Associated with Lithium Response in Bipolar Disorder: An Integrative Review and In Silico Protein-Protein Interaction Analysis. [PDF]
Ejiohuo O, Szczepankiewicz A.
europepmc +1 more source
An integrated phenomics–genomics framework captures dynamic salt‐stress responses in laboratory‐grown cotton seedlings through time‐series hyperspectral imaging and non‐destructive i‐trait extraction. Hierarchical screening identifies biologically relevant, heritable, and non‐redundant traits for high‐resolution GWAS, identifying GhST7.
Bowei Xu +11 more
wiley +1 more source
Uncovering the role of genetic polymorphisms in cervical insufficiency. [PDF]
Kalinderi K +3 more
europepmc +1 more source
Robust and Compatible Ferroelectric Memories with Polycrystalline TiO2 Channel for 3D Integration
Robust and monolithic 3D compatible ferroelectric memories are realized using the polycrystalline TiO2 channel‐based FeFET. The review covers physical mechanisms of the TiO2 channel FeFET, quantitative benchmarking, and advanced planar/vertical architectures for monolithic 3D integration based on HfO2‐TiO2 gate stack, offering a roadmap for reliable ...
Xujin Song +10 more
wiley +1 more source
The distinct effects of metabolic syndrome on negative symptoms and on antipsychotic therapy of schizophrenia involve insular volume, functional connectivity, and genetic polymorphisms. [PDF]
Zhou J +14 more
europepmc +1 more source
This work electrically characterizes sixteen logic gates built from three‐independent‐gate reconfigurable transistors fabricated on full‐scale 300 mm wafers using the industrial 22 nm fully depleted FDSOI process of GlobalFoundries. Static and time‐resolved measurements confirm correct operation, including a 1‐bit adder and reconfigurable AOI/OAI ...
Juan P. Martinez +12 more
wiley +1 more source
Genetic Polymorphisms in <i>SCN1A</i> Gene (rs6432860) and Pharmacoresistance to Antiepileptic Drugs Among Jordanian Patients with Epilepsy. [PDF]
Al-Sadir H +6 more
europepmc +1 more source

