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Genetic predisposition to longer lifespan, lifestyle factors, and all-cause mortality: a 17-year prospective cohort study

Tynkkynen NP, Joensuu L, Herranen P, Kaprio J, Törmäkangas T, Sillanpää E.   +5 more
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Physical Frailty, Genetic Predisposition, and Incident Parkinson Disease

JAMA Neurology, 2023
ImportanceCross-sectional evidence implicates high prevalent frailty in patients with Parkinson disease (PD), whereas the longitudinal association remains unknown.ObjectivesTo examine the longitudinal association of the frailty phenotype with the development of PD and to explore the modification role of genetic risk of PD in such an association.Design,
Zekun, Zheng, Yanling, Lv, Shuang, Rong, Taoping, Sun, Liangkai, Chen   +4 more
openaire   +3 more sources

Genetic predisposition to coronary artery disease

Current Opinion in Cardiology, 2001
Understanding the genetic basis of coronary artery disease (CAD) can improve management and prevention. Family and twin studies, animal models and gene association studies support a genetic basis for CAD. Genes contribute to CAD development and progression, and response to risk factor modification and lifestyle choices.
M. Scheuner
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Genetic predisposition to iatrogenic Creutzfeldt-Jakob disease

The Lancet, 1991
The spongiform encephalopathy Creutzfeldt-Jakob disease (CJD) has been transmitted to man via administration of growth hormone and gonadotropin extracted from large pooled batches of human cadaveric pituitary glands. In the UK, 1908 individuals were exposed to potentially contaminated growth hormone, of whom 6 have so far manifested CJD. Examination of
Mark S. Palmer, A. J. Dryden, John Collinge   +2 more
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Possible Neurophysiological Markers of Genetic Predisposition to Alzheimer’s Disease

Dementia and Geriatric Cognitive Disorders, 1998
Visual-evoked potentials (VEP) to a flash were studied in the first-order relatives of patients with Alzheimer’s disease (AD) (mean age 38.2 ± 2.6 years) in comparison with the patients (mean age 61.9 ± 1.4 years) and age-matched normal controls. It was found that in the relatives of AD patients the latencies of N2, P3, N3 components were delayed ...
V.F. Fokin, N.I. Voskresenskaia, N.V. Ponomareva, N.D. Selesneva   +3 more
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Geographical similarity and differences in the burden and genetic predisposition of NAFLD

Hepatology, 2022
NAFLD has become a major public health problem for more than 2 decades with a growing prevalence in parallel with the epidemic of obesity and type 2 diabetes (T2D).
T. Yip, E. Vilar‐Gomez, S. Petta, Y. Yılmaz, G. Wong, L. Adams, V. de Lédinghen, S. Sookoian, V. Wong   +8 more
semanticscholar   +1 more source

Ethical aspects of genetic predisposition to disease

1991
P. Grandjean
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