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Genetic Predisposition to Parkinson’s Disease and Cancer

Current Cancer Drug Targets, 2014
Parkinson's disease (PD) and cancer are often thought of as two sides of the same coin. At first glance, cancer and PD appear to have little in common. PD is caused by the degeneration of dopaminergic neurons, whereas cancer results from the uninhibited growth of tumor cells. Increasing numbers of genetic studies suggest that the pathogenesis of PD and
Qing Lin   +4 more
openaire   +3 more sources

Coronavirus: Pure Infectious Disease or Genetic Predisposition

2021
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which causes novel coronavirus disease (COVID-19), is the seventh pathogenic coronavirus recently discovered in December 2019 in Wuhan, China. To date, our knowledge about its effect on the human host remains limited.
Farzaneh Darbeheshti   +9 more
openaire   +3 more sources

Genetic predisposition in type 2 diabetes: A promising approach toward a personalized management of diabetes

Clinical Genetics, 2020
Diabetes mellitus, also known simply as diabetes, has been described as a chronic and complex endocrine metabolic disorder that is a leading cause of death across the globe. It is considered a key public health problem worldwide and one of four important
M. Sirdah, N. Reading
semanticscholar   +1 more source

GENETIC PREDISPOSITION TO DRUG-INDUCED LIVER DISEASE

Gastroenterology Clinics of North America, 1995
Rarely do otherwise safe drugs administered at recommended doses produce liver damage that may progress to liver failure and death. Because we are generally unable to identify the patients most susceptible to this "idiosyncratic" form of toxicity, many potentially useful medications are not made available to patients. The most promising developments in
Paul B. Watkins, Robert J. Fontana
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Genetic predisposition to environmental induced diseases

Environmental Toxicology and Pharmacology, 1997
It is argued that genetic predispositions to environmentally induced illness are common in the general population. Yet, despite this, recognition assessment of the nature and magnitude of such predispositions has generally not been the object of environmental health research.
openaire   +3 more sources

[Genetic predisposition for Alzheimer's disease].

Therapeutische Umschau. Revue therapeutique, 1996
Alzheimer's disease comprises senile and presenile dementia. Aetiologically the disease is heterogeneous but has common clinical and pathological characteristics. Furthermore, in patients with a family history of dementia, its incidence is higher than in the general population.
M, Staufenbiel, E, Pombo-Villar
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Genetic Predisposition to Hypertension and Cardiovascular Disease

2003
Essential hypertension occurs in individuals with a genetic predisposition who respond abnormally to environmental changes. A complex interplay of a number of genetic alterations and environmental factors is involved in the pathogenesis of hypertension.
Toshio Ogihara   +2 more
openaire   +2 more sources

Preimplantation diagnosis for diseases with genetic predisposition and nondisease testing

Expert Review of Molecular Diagnostics, 2002
Preimplantation genetic diagnosis has become a method of choice in genetic practices. The present experience includes thousands of clinical cases of preimplantation genetic diagnosis, demonstrating the safety, accuracy and reliability of the technique and its clinical relevance for those at-risk couples who cannot accept traditional methods for ...
Yury Verlinsky, Anver Kuliev
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GENETIC FACTORS AND PREDISPOSITION TO DISEASE

This article reviews genetic factors that influence susceptibility to various diseases, including both hereditary and multifactorial disorders. The study relies on the analysis of existing data and the results of meta-analyses to substantiate the significance of genetic predisposition in disease pathogenesis.
Karimov Abduhalim Abdurozikovich   +1 more
openaire   +1 more source

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