Results 81 to 90 of about 88,056,303 (299)

Genetic predisposition to celiac disease

, 2009
5 Abstract Coeliac disease is a chronic intestinal autoimmune desease that is diagnosed in genetically predisposed people. This disease is characterized by inadequate immune response to gluten, which is contained in some cereals.
Cibuľová, Anna
core  

microRNA‐7‐5p and α‐Synuclein SAA Predict Parkinson's Disease Phenoconversion

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Corroborate blood neuron‐derived extracellular vesicle (NDEV) alpha‐synuclein (αSyn), the CSF αSyn seed amplification assay (αSyn‐SAA), and blood microRNA‐7‐5p (miR‐7‐5p) as markers for Parkinson's disease (PD) phenoconversion and determine if combining these markers would help select subjects who would be more likely to phenoconvert.
Shayan Zadegan, Praveen Velammal, Kanmani Muthiah, Madhu Jatty, Christopher Adams   +4 more
wiley   +1 more source

Safety of Prescription Nonsteroidal Anti‐inflammatory Drugs in Adults With Inflammatory Bowel Disease: Data From a Large Administrative Claims Cohort

Arthritis Care &Research, EarlyView.
Objective The concern that nonsteroidal anti‐inflammatory drugs (NSAIDs) may precipitate flares of inflammatory bowel disease (IBD) has limited their use in managing musculoskeletal symptoms in those with IBD, but safety data are mixed. Methods This retrospective cohort study included patients with IBD aged at least 18 years from Optum's deidentified ...
Adam S. Mayer, Rui Xiao, Meenakshi Bewtra, Michael D. George, Pamela F. Weiss   +4 more
wiley   +1 more source

From Adult to Adolescent: Alignment in Clinical Trials and Outcomes in Axial Spondyloarthritis

Arthritis Care &Research, EarlyView.
Spondyloarthritis (SpA) is a group of chronic inflammatory diseases encompassing axial and peripheral forms, with up to 20% of patients developing symptoms before age 16. Despite this substantial pediatric burden, treatment options for juvenile‐onset SpA (JSpA), particularly those with axial disease (axJSpA), remain limited.
Pamela F. Weiss, Judith A. Smith, Robert A. Colbert, Erin Treemarcki, Michael H. Weisman, Walter P. Maksymowych, Hermine I. Brunner, for the Childhood Arthritis and Rheumatology Research Alliance, Spondyloarthritis Research and Treatment Network, and Pediatric Rheumatology Collaborative Study Group Advisory Council   +9 more
wiley   +1 more source

Fecal calprotectin in first-degree relatives of patients with ulcerative colitis

, 2007
OBJECTIVES: The pathogenesis of inflammatory bowel disease seems to depend on the combination of genetic and environmental factors. To evaluate genetic susceptibility, one approach is to search for specific markers in apparently unaffected family ...
Ancarani, Francesca, Montalto, Massimo, Cammarota, Giovanni, Gasbarrini, Antonio, Covino, Marcello, Gasbarrini, Giovanni Battista, Armuzzi, Alessandro, Manna, Raffaele, Santoro, Luca, Curigliano, Valentina   +9 more
core   +1 more source

Association between genetic predisposition and disease burden of stroke in China: a genetic epidemiological study. [PDF]

Lancet Reg Health West Pac, 2023
Huang Q, Lan X, Chen H, Li H, Sun Y, Ren C, Xing C, Bo X, Wang J, Jin X, Song L.   +10 more
europepmc   +1 more source

GENETIC FACTORS AND PREDISPOSITION TO DISEASE

This article reviews genetic factors that influence susceptibility to various diseases, including both hereditary and multifactorial disorders. The study relies on the analysis of existing data and the results of meta-analyses to substantiate the significance of genetic predisposition in disease pathogenesis.
Karimov Abduhalim Abdurozikovich, Hamidova Zebiniso Hikmatovna   +1 more
openaire   +2 more sources

GENETIC MARKERS OF PREDISPOSITION TO METABOLIC DISEASES

Vestnik APK Verhnevolzh`ia, 2023
В эпоху активного развития цифровых технологий в животноводстве всё большую актуальность стали приобретать современные методы молекулярной генетики, позволяющие диагностировать целый комплекс хозяйственно полезных признаков у животных. Вместе с тем, маркер-ориентированная селекция открывает возможности для прогнозирования предрасположенности к ...
openaire   +1 more source

Longitudinal Changes in Adiposity After a Youth Sport‐Related Knee Injury: Informing Posttraumatic Osteoarthritis Prevention

Arthritis Care &Research, EarlyView.
Objective Youth who experience a sport‐related knee injury have elevated odds of becoming overweight or developing obesity in 3 to 10 years, compounding their risk for posttraumatic osteoarthritis (PTOA). To inform prevention strategies, this study compared patterns of adiposity change between youth with a sport‐related knee injury and uninjured youth ...
Justin M. Losciale, Nuria E. J. Jansen, Christina Y. Le, Leo Lu, Hui Xie, Marienke van Middelkoop, Jackie L. Whittaker   +6 more
wiley   +1 more source

Distribution of genetic diversity in wild European populations of prickly lettuce (Lactuca serriola): implications for plant genetic resources management [PDF]

, 2010
Genetic variation in Lactuca serriola, the closest wild relative of cultivated lettuce, was studied across Europe from the Czech Republic to the United Kingdom, using three molecular marker systems, simple sequence repeat (SSR, microsatellites), AFLP and
Sretenovic Rajicic, T., Dehmer, K.J., Hintum, T.J.L., van, Treuren, R., van, Linden, C.G., van der, Wiel, C.C.M., van de   +5 more
core   +1 more source