Results 71 to 80 of about 208,174 (208)

Ryanodine receptor gene is a candidate for predisposition to malignant hyperthermia

, 1990
Malignant hyperthermia (MH) is a potentially lethal condition in which sustained muscle contracture, with attendant hypercatabolic reactions and elevation in body temperature, are triggered by commonly used inhalational anaesthetics and skeletal muscle ...
D. H. MACLENNAN, C. DUFF, AND R. G. WORTON RYANODINE RECEPTOR GENE IS A. CANDIDATE FOR PREDISPOSITION TO MALIGNANT H.Y.P.E.R.T.H.E.R.M.I.A. NATURE, M. PHILLIPS, R. G. KORNELUK, J. FUJII, W. FRODIS, B. A. BRITT, ZORZATO, Francesco   +8 more
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Anti-Saccharomyces cerevisiae antibodies in patients with inflammatory bowel disease and their first-degree relatives: Potential clinical value [PDF]

, 2002
Anti-Saccharomyces cerevisiae antibodies (ASCA) have been described as specific markers in Crohn's disease and their healthy first-degree relatives. 171 patients with Crohn's disease, their 105 first-degree relatives, 145 patients with ulcerative colitis
Török, H.-P., Hoelscher, Michael, Folwaczny, Christian, Vilsmaier, F., Herbinger, K. H., Glas, J.   +5 more
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A tagging polymorphism in fat mass and obesity-associated (FTO) gene is associated with sepsis status in children

Romanian Journal of Internal Medicine
Sepsis is one of the most common causes of death in patients admitted to intensive care units (ICUs). The development of sepsis is significantly influenced by genetic predisposition.
Jabandziev Petr, Hubacek Jaroslav Alois, Michalek Jaroslav, Jouza Martin, Papez Jan, Pecl Jakub, Slaba Katerina, Slaby Ondrej, Urik Milan, Aulicka Stefania, Kunovsky Lumir, Michalek Jaroslav, Dominik Petr, Kratochvil Milan, Klucka Jozef, Stourac Petr   +15 more
doaj   +1 more source

GENETIC MARKERS OF PREDISPOSITION TO METABOLIC DISEASES

Vestnik APK Verhnevolzh`ia, 2023
В эпоху активного развития цифровых технологий в животноводстве всё большую актуальность стали приобретать современные методы молекулярной генетики, позволяющие диагностировать целый комплекс хозяйственно полезных признаков у животных. Вместе с тем, маркер-ориентированная селекция открывает возможности для прогнозирования предрасположенности к ...
openaire   +1 more source

Cerebral small vessel disease in middle age and genetic predisposition to late-onset Alzheimer’s Disease

, 2017
INTRODUCTION:Cerebral small vessel disease (CSVD) is associated with late-onset Alzheimer's disease (LOAD) and might contribute to the relationship between apolipoprotein E ε4 (APOE ε4) and LOAD, in older people.
Ritchie, Karen, John T. O'Brien, Katie Wells, Ritchie, Craig W., Waldman, Adam, Stefaniak, James D., Karen Ritchie, Mak, Elijah, Elijah Mak, O'Brien, John, O'brien, John T., Su, Li, Stefaniak, James, Adam Waldman, Wells, Katie, Ritchie, Craig, Craig W. Ritchie, Sheikh Bahaei, Nasim, James D. Stefaniak, Li Su, Nasim Sheikh‐Bahaei, Bahaei, Nasim Sheikh   +21 more
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Association Between IL-4 and IL-6 Expression Variants and Gastric Cancer Among Portuguese Population

GE: Portuguese Journal of Gastroenterology, 2015
Introduction: Multiple studies have reported strong associations between Helicobacter pylori (Hp) inflammation and gastric cancer (GC) development. Altered expressions of pro/anti-inflammatory cytokines have a crucial role in Hp and GC proliferation ...
Ana Maria Sampaio, Sandra Caramujo Balseiro, Maria Reis Silva, Ana Alarcão, Maria João d’Aguiar, Teresa Ferreira, Lina Carvalho   +6 more
doaj   +1 more source

Combinatorial Conflicting Homozygosity (CCH) analysis enables the rapid identification of shared genomic regions in the presence of multiple phenocopies.

, 2015
The ability to identify regions of the genome inherited with a dominant trait in one or more families has become increasingly valuable with the wide availability of high throughput sequencing technology.
Neild, GH, Connor, TM, Levine, AP, Maxwell, PH, Gale, DP, Oygar, DD, Segal, AW   +6 more
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Advancing allergic rhinitis research through phenome-wide association studies: Insights from known genetic loci

World Allergy Organization Journal
Background: Allergic rhinitis (AR) is a common chronic respiratory disease that can lead to the development of various other conditions. Although genetic risk loci associated with AR have been reported, the connections between these loci and AR ...
Xingling Tan, MD, Zhouyouyou Xiao, MB, Yao Wen, MD, Han Liu, MD, Wei Yu, MD   +4 more
doaj   +1 more source

GENETIC FACTORS AND PREDISPOSITION TO DISEASE

This article reviews genetic factors that influence susceptibility to various diseases, including both hereditary and multifactorial disorders. The study relies on the analysis of existing data and the results of meta-analyses to substantiate the significance of genetic predisposition in disease pathogenesis.
Karimov Abduhalim Abdurozikovich, Hamidova Zebiniso Hikmatovna   +1 more
openaire   +2 more sources

Genetic risk variants in intestinal inflammatory disorders

, 2010
PhDThis thesis includes work on the genetics of intestinal inflammatory disorders, concentrating on coeliac disease and Crohn’s disease. It explores how common genetic variants influence risk of complex phenotypes including immunological intolerance to
Dubois, Patrick Charles Alexander
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