Results 21 to 30 of about 213,537 (298)
Nonmutagenic carcinogens induce intrachromosomal recombination in dividing yeast cells. [PDF]
, 1993 A large number of animal and human carcinogens without apparent genotoxic activity exist (nonmutagenic carcinogens) that are difficult or impossible to detect with the currently used short-term tests.
Schiestl, RH
core +2 more sources
G3: Genes, Genomes, Genetics, 2019 Meiotic recombination generates genetic diversity but in most species the number of crossovers per meiosis is limited. Previous modeling studies showed that increasing recombination can enhance response to selection.
Elise Tourrette +3 more
doaj +1 more source
PLoS ONE, 2020 Characterizing meiotic recombination rates across the genomes of nonhuman primates is important for understanding the genetics of primate populations, performing genetic analyses of phenotypic variation and reconstructing the evolution of human ...
Cheng Xue +7 more
doaj +1 more source
SUMOylation of Rad52-Rad59 synergistically change the outcome of mitotic recombination [PDF]
, 2016 Homologous recombination (HR) is essential for maintenance of genome stability through double-strand break (DSB) repair, but at the same time HR can lead to loss of heterozygosity and uncontrolled recombination can be genotoxic.
Lisby, Michael, Silva, Sonia
core +1 more source
Multiple mating but not recombination causes quantitative increase in offspring genetic diversity for varying genetic architectures. [PDF]
PLoS ONE, 2012 Explaining the evolution of sex and recombination is particularly intriguing for some species of eusocial insects because they display exceptionally high mating frequencies and genomic recombination rates. Explanations for both phenomena are based on the
Olav Rueppell +2 more
doaj +1 more source
The extent of error-prone replication-restart by homologous recombination is controlled by Exo1 and checkpoint proteins [PDF]
, 2014 Genetic instability, a hallmark of cancer, can occur when the replication machinery encounters a barrier. The intra-S phase checkpoint maintains stalled replication forks in a replication-competent configuration by phosphorylating replisome components ...
Ahn +80 more
core +2 more sources
A high-resolution single nucleotide polymorphism genetic map of the mouse genome.
PLoS Biology, 2006 High-resolution genetic maps are required for mapping complex traits and for the study of recombination. We report the highest density genetic map yet created for any organism, except humans.
Sagiv Shifman +6 more
doaj +1 more source
Recombination and Population Mosaic of a Multifunctional Viral Gene, Adeno-Associated Virus cap [PDF]
, 2008 Homologous recombination is a dominant force in evolution and results in genetic mosaics. To detect evidence of recombination events and assess the biological significance of genetic mosaics, genome sequences for various viral populations of reasonably ...
Danos, O, Myers, R, Takeuchi, Y
core +3 more sources
Genetic recombination as DNA repair [PDF]
, 2015 AbstractMaintenance of sexual reproduction and genetic recombination imposes physiological costs when compared to parthenogenic reproduction, most prominently: for maintaining the corresponding (molecular) machinery, for finding a mating partner, and through the decreased fraction of females in a population, which decreases the reproductive capacity ...
Parkhomchuk, Dmitri +2 more
openaire +2 more sources
Genetic Recombination in Caulobacter [PDF]
Journal of General Microbiology, 1972 SUMMARY: Auxotrophic, phage-resistant and streptomycin-resistant mutants of Caulobacter were used to demonstrate genetic recombination in this genus. Forty of a possible 170 mating pairs gave recombinant frequencies of from 100 to 1000 times greater than reversion frequencies for the markers used.
J. D. Jollick, Ella M. Schervish
openaire +2 more sources