Results 21 to 30 of about 330,144 (256)

Allopolyploidization increases genetic recombination in the ancestral diploid D genome during wheat evolution

Crop Journal, 2022
Genetic recombination produces new allelic combinations, thereby introducing variation for domestication. Allopolyploidization has increased the evolutionary potential of hexaploid common wheat by conferring the advantages of heterosis and gene ...
Hongshen Wan, Jun Li, Shengwei Ma, Fan Yang, Liang Chai, Zehou Liu, Qin Wang, Zongjun Pu, Wuyun Yang   +8 more
doaj   +1 more source

Assessing by Modeling the Consequences of Increased Recombination in Recurrent Selection of Oryza sativa and Brassica rapa

G3: Genes, Genomes, Genetics, 2019
Meiotic recombination generates genetic diversity but in most species the number of crossovers per meiosis is limited. Previous modeling studies showed that increasing recombination can enhance response to selection.
Elise Tourrette, Rex Bernardo, Matthieu Falque, Olivier C. Martin   +3 more
doaj   +1 more source

Multiple mating but not recombination causes quantitative increase in offspring genetic diversity for varying genetic architectures. [PDF]

PLoS ONE, 2012
Explaining the evolution of sex and recombination is particularly intriguing for some species of eusocial insects because they display exceptionally high mating frequencies and genomic recombination rates. Explanations for both phenomena are based on the
Olav Rueppell, Stephen Meier, Roland Deutsch   +2 more
doaj   +1 more source

A high-resolution single nucleotide polymorphism genetic map of the mouse genome.

PLoS Biology, 2006
High-resolution genetic maps are required for mapping complex traits and for the study of recombination. We report the highest density genetic map yet created for any organism, except humans.
Sagiv Shifman, Jordana Tzenova Bell, Richard R Copley, Martin S Taylor, Robert W Williams, Richard Mott, Jonathan Flint   +6 more
doaj   +1 more source

Reduced meiotic recombination in rhesus macaques and the origin of the human recombination landscape.

PLoS ONE, 2020
Characterizing meiotic recombination rates across the genomes of nonhuman primates is important for understanding the genetics of primate populations, performing genetic analyses of phenotypic variation and reconstructing the evolution of human ...
Cheng Xue, Navin Rustagi, Xiaoming Liu, Muthuswamy Raveendran, R Alan Harris, Manjunath Gorentla Venkata, Jeffrey Rogers, Fuli Yu   +7 more
doaj   +1 more source

Random-sequence genetic oligomer pools display an innate potential for ligation and recombination

eLife, 2018
Recombination, the exchange of information between different genetic polymer strands, is of fundamental importance in biology for genome maintenance and genetic diversification and is mediated by dedicated recombinase enzymes. Here, we describe an innate
Hannes Mutschler, Alexander I Taylor, Benjamin T Porebski, Alice Lightowlers, Gillian Houlihan, Mikhail Abramov, Piet Herdewijn, Philipp Holliger   +7 more
doaj   +1 more source

Identification and manipulation of the molecular determinants influencing poliovirus recombination.

PLoS Pathogens, 2013
The control and prevention of communicable disease is directly impacted by the genetic mutability of the underlying etiological agents. In the case of RNA viruses, genetic recombination may impact public health by facilitating the generation of new viral
Charles Runckel, Oscar Westesson, Raul Andino, Joseph L DeRisi   +3 more
doaj   +1 more source

Homologous Recombination in Clostridioides difficile Mediates Diversification of Cell Surface Features and Transport Systems

mSphere, 2020
Illness caused by the pathogen Clostridioides difficile is widespread and can range in severity from mild diarrhea to sepsis and death. Strains of C. difficile isolated from human infections exhibit great genetic diversity, leading to the hypothesis that
Hannah D. Steinberg, Evan S. Snitkin
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source