Results 61 to 70 of about 3,312,951 (387)
FoxO1 signaling in B cell malignancies and its therapeutic targeting
FEBS Letters, EarlyView.FoxO1 has context‐specific tumor suppressor or oncogenic character in myeloid and B cell malignancies. This includes tumor‐promoting properties such as stemness maintenance and DNA damage tolerance in acute leukemias, or regulation of cell proliferation and survival, or migration in mature B cell malignancies.
Krystof Hlavac +3 more
wiley +1 more source
Optimal Recombination in Genetic Algorithms [PDF]
, 2013 This paper surveys results on complexity of the optimal recombination problem (ORP), which consists in finding the best possible offspring as a result of a recombination operator in a genetic algorithm, given two parent solutions.
Eremeev, Anton V., Kovalenko, Julia V.
core
Coalescence, genetic diversity in sexual populations under selection [PDF]
, 2013 In sexual populations, selection operates neither on the whole genome, which is repeatedly taken apart and reassembled by recombination, nor on individual alleles that are tightly linked to the chromosomal neighborhood. The resulting interference between
Kessinger, Taylor A. +2 more
core +2 more sources
Molecular Genetics of Recombination [PDF]
, 2007 Genetics of Recombination in the Model Bacterium Escherichia Coli.- Homologous Recombination in Low dC + dG Gram-Positive Bacteria.- The Bacterial RecA Protein: Structure, Function, and Regulation.- Biochemistry of Eukaryotic Homologous Recombination.- DNA helicases in recombination.- Holliday Junction Resolution.- Replication forks and replication ...
Andrés Aguilera, Rodney Rothstein
openaire +2 more sources
Genetic Recombination and Cryptosporidium hominis Virulent Subtype IbA10G2
Emerging Infectious Diseases, 2013 Little is known about the emergence and spread of virulent subtypes of Cryptosporidium hominis, the predominant species responsible for human cryptosporidiosis. We conducted sequence analyses of 32 genetic loci of 53 C.
Na Li +6 more
semanticscholar +1 more source
FEBS Letters, EarlyView.Metabolic dysfunction‐associated steatotic liver disease (MASLD) affects nearly one‐third of the global population and poses a significant risk of progression to cirrhosis or liver cancer. Here, we discuss the roles of hepatic dendritic cell subtypes in MASLD, highlighting their distinct contributions to disease initiation and progression, and their ...
Camilla Klaimi +3 more
wiley +1 more source
Genetic Recombination as a Chemical Reaction Network
, 2015 The process of genetic recombination can be seen as a chemical reaction network with mass-action kinetics. We review the known results on existence, uniqueness, and global stability of an equilibrium in every compatibility class and for all rate ...
Hofbauer, Josef, Müller, Stefan
core +1 more source
The Landscape of Realized Homologous Recombination in Pathogenic Bacteria [PDF]
, 2015 Recombination enhances the adaptive potential of organisms by allowing genetic variants to be tested on multiple genomic backgrounds. Its distribution in the genome can provide insight into the evolutionary forces that underlie traits, such as the ...
Didelot, X +6 more
core +2 more sources
G3: Genes, Genomes, Genetics, 2016 Meiotic recombination is a genetic process that is critical for proper chromosome segregation in many organisms. Despite being fundamental for organismal fitness, rates of crossing over vary greatly between taxa.
Chad M. Hunter +3 more
doaj +1 more source
Genetic Recombination in Lactobacilli
Biotechnology & Biotechnological Equipment, 2001 ABSTRACTAn interspecies genetic recombination by fusion of protoplasts of antibiotic-resistant clones of lactobacilli: Lactobacillus delbrueckii subsp. bulgaricus, Lactobacillus helveticus, Lactobacillus casei, and Lactobacillus plantarum has been accomplished.
I.D. Murgov, Z.R. Denkova
openaire +2 more sources