Results 61 to 70 of about 320,836 (246)

ATP13A2 is involved in intracellular polyamine transport in lung epithelial cells

FEBS Open Bio, EarlyView.
Spermidine transport in lung epithelial cells involves the polyamine transporter ATP13A2. Cell proliferation is associated with the upregulation of ATP13A2. Polyamines are present in all living cells and are implicated in various crucial cellular processes such as proliferation, apoptosis and autophagy.
Yuta Hatori, Kohei Kawabata, Takanori Kubo, Takeo Kitazawa, Sae Kanai, Madoka Iwashita, Ami Hayashi, Hiroyuki Nishi, Mikihisa Takano   +8 more
wiley   +1 more source

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

FEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada, Mina Iwaki, Kyosuke Hagiri, Rei Izumi, Masahiko Harata, Chihiro Horigome   +5 more
wiley   +1 more source

Systemic T Cell Receptor Profiling Reveals Adaptive Immune Activation and Potential Immune Signatures of Diagnosis and Brain Atrophy in Epilepsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Epilepsy is increasingly associated with immune dysregulation and inflammation. The T cell receptor (TCR), a key mediator of adaptive immunity, shows repertoire alterations in various immune‐mediated diseases. The unique TCR sequence serves as a molecular barcode for T cells, and clonal expansion accompanied by reduced overall TCR ...
Yong‐Won Shin, Sang Bin Hong, Yong Woo Shin, Inpyeong Hwang, Jaeseong Oh, Jihyeon Choi, Narae Kim, Jangsup Moon, Keun‐Hwa Jung, Kyung‐Il Park, Ki‐Young Jung, Kon Chu, Sang Kun Lee   +12 more
wiley   +1 more source

Genome-wide atlas of loci involved in chromosomal recombination in common wheat

BMC Plant Biology
Chromosomal recombination is a pivotal biological mechanism for generating novel genetic diversity, essential for plant breeding and genetic research endeavors.
Yanchun Peng, Xinru Lyu, Dengan Xu, Zunjie Wang, Xianchun Xia, Yuanfeng Hao, Hongya Wu, Wujun Ma   +7 more
doaj   +1 more source

Copy Number Variants and Their Association With Intracerebral Hemorrhage Risk: A Case–Control Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Intracerebral Hemorrhage (ICH) is a leading cause of morbidity and mortality worldwide and lacks effective therapeutic interventions. Despite previous studies, the genetic underpinnings of ICH remain poorly understood. We sought to investigate the role of copy number variants (CNVs) in ICH pathophysiology to identify novel ...
Savvina Prapiadou, Carl D. Langefeld, Padmini Sekar, Mary Comeau, Timothy Howard, Tamara N. Kimball, Chen Bowang, Hyacinth I. Hyacinth, Jonathan Rosand, Christopher D. Anderson, Caspar Grond‐Ginsbach, Daniel Woo, Stacie L. Demel   +12 more
wiley   +1 more source

Fast inference of genetic recombination rates in biobank scale data. [PDF]

Genome Res, 2023
Naseri A, Yue W, Zhang S, Zhi D.
europepmc   +1 more source

Challenges during Flash Lamp Annealing of Aerosol‐Deposited Barium Titanate Films

Advanced Engineering Materials, EarlyView.
Aerosol deposition is used to rapidly deposit barium titanate films with thicknesses ranging from 2 to 16 μm at room temperature, eliminating the need for further densification. However, to recover the electromechanical properties, annealing is required, which limits the usage of temperature‐sensitive substrates.
Michel Kuhfuß, Juliette Cardoletti, Udo R. Eckstein, Shaoxiong Xie, Alexander Martin, Ken‐ichi Kakimoto, Sebastjan Glinšek, Kyle G. Webber   +7 more
wiley   +1 more source

Use of oval conidia as a tool to assess the genetic transfer among Colletotrichum sublineolum mutants

Brazilian Archives of Biology and Technology, 2010
The aim of this study was to assess oval conidia production in mutants for the reductase nitrate gene in C. sublineolum and verify the possibility of using them as a tool to transfer the genetic material in this species.
Maria Paula Nunes, Ednéia Aparecida de Souza-Paccola, Gisele Maria Andrade-Nóbrega, Luzia Doretto Paccola-Meirelles   +3 more
doaj   +1 more source

Consequences of Genetic Recombination on Protein Folding Stability. [PDF]

J Mol Evol, 2023
Del Amparo R, González-Vázquez LD, Rodríguez-Moure L, Bastolla U, Arenas M.   +4 more
europepmc   +1 more source

Editor's evaluation: Combining genotypes and T cell receptor distributions to infer genetic loci determining V(D)J recombination probabilities

, 2021
Benny Chain
openalex   +1 more source