Results 51 to 60 of about 5,434,712 (302)
ABSTRACT Background Numerous international studies have reported declines in new cancer diagnoses, delayed diagnoses and disruptions in cancer treatment following the implementation of COVID‐19 pandemic public health measures, raising concerns that these effects may ultimately contribute to increased cancer mortality.
Friederike Erdmann +8 more
wiley +1 more source
Ecological modernization versus sustainable development: the case of genetic modification regulation in New Zealand [PDF]
Ecological modernization and sustainable development are the two dominant paradigms in environmental policy. This paper assesses the implications of competing understandings of ecological modernization and sustainable development using the case of ...
Wright, Jeanette Marie +3 more
core +1 more source
Chromatin complex dependencies reveal targeting opportunities in leukemia
Epigenetic regulators are potential therapeutic drug targets in leukemia. Here, the authors perform combinatorial CRISPR knockouts to test gene-gene pairings in leukemia cells to discover compensatory non-lethal or synergistic lethal combinations with ...
Fadi J. Najm +11 more
doaj +1 more source
Genetic regulation of plasmid transfer
[No abstract available]
Pekhov A.P. +2 more
openaire +4 more sources
ABSTRACT Pediatric intramedullary low‐grade gliomas (PIMLGGs) are rare neoplasms that present unique clinical and management challenges. Although surgery remains the primary tool for tissue diagnosis and decompression, complete gross‐total resection is frequently unfeasible due to the infiltrative nature of these lesions.
Olga M. Sergeenko +5 more
wiley +1 more source
Metabolic profiling of serum and urine in preeclampsia and gestational diabetes in early pregnancy
PE and GDM are two major metabolic diseases affecting pregnancy. Individuals suffering from GDM are at an increased risk of developing PE in later gestational stages.
Nupur Rani Agarwal +3 more
doaj +1 more source
ABSTRACT Pediatric refractory immune thrombocytopenia (rITP) is generally characterized by persistent thrombocytopenia and failure to achieve a sustained response to multiple standard therapies. We report a 4‐year‐old female with congenital tufting enteropathy, post‐intestinal transplant patient on immunosuppressants, who developed severe rITP ...
Sarah Hsieh +4 more
wiley +1 more source
ABSTRACT Background Outcomes in relapsed or refractory pediatric and AYA bone sarcomas remain poor, and the impact of early referral to specialized sarcoma centers on survival is unclear. Early centralization of care may improve local and systemic treatment quality, but evidence in this population is limited.
Justyna Antoniuk‐Majchrzak +9 more
wiley +1 more source
Context-Dependent Genetic Regulation
Cells process extra-cellular signals with multiple layers of complex biological networks. Due to the stochastic nature of the networks, the signals become significantly noisy within the cells and in addition, due to the nonlinear nature of the networks ...
Herbert M. Sauro +3 more
core +1 more source
Genetic Regulation of the Growth Plate [PDF]
The epiphyseal growth plate consists of a layer of cartilage present only during the growth period and vanishes soon after puberty in long bones. It is divided to three well-defined zones, from epiphyses; resting, proliferative, and hypertrophic zones.
Karimian, Elham +2 more
openaire +3 more sources

