Results 41 to 50 of about 681,929 (290)

Characterizing Parental Concerns About Lasting Impacts of Treatment in Children With B‐Acute Lymphoblastic Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background B‐acute lymphoblastic leukemia (B‐ALL) is the most common pediatric cancer, and while most children in high‐resource settings are cured, therapy carries risks for long‐term toxicities. Understanding parents’ concerns about these late effects is essential to guide anticipatory support and inform evolving therapeutic approaches ...
Kellee N. Parker, Sarah W. Alexander, Lisa M. Jacola, Kimberly A. Buff, Kyobin Hwang, Elham Hashemi, Gregory Stoddard, Lindsay A. Jibb   +7 more
wiley   +1 more source

Valuing animal genetic resources: lessons from plant genetic resources

Ecological Economics, 2003
Abstract A growing body of theoretical and empirical studies has examined issues relating to the valuation, utilization, and management of plant genetic resources (PGRs). This paper attempts to summarize relevant lessons from this literature for animal genetic resources.
Gollin, Douglas, Evenson, R.
openaire   +2 more sources

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Local breeds and pastoral farming on the North Mediterranean shore: a univocal coevolution? An example of dairy sheep farming systems in Corsica (France) and Thessaly (Greece)

Genetic Resources, 2021
Using local resources for ruminant feeding is a way to achieve agroecological production in pastoral farming systems. In North Mediterranean countries, sheep farming systems have evolved towards more intensive systems in lowland and hilly areas, whereas
Lola Perucho, Ioannis Hadjigeorgiou, Anne Lauvie, Charles-Henri Moulin, Jean-Christophe Paoli, Christina Ligda   +5 more
doaj   +1 more source

An intracellular transporter mitigates the CO2‐induced decline in iron content in Arabidopsis shoots

FEBS Letters, EarlyView.
This study identifies a gene encoding a transmembrane protein, MIC, which contributes to the reduction of shoot Fe content observed in plants under elevated CO2. MIC is a putative Fe transporter localized to the Golgi and endosomal compartments. Its post‐translational regulation in roots may represent a potential target for improving plant nutrition ...
Timothy Mozzanino, Meijie Li, Cécile Fizames, Mattia Adamo, Laurence Lejay, Christian Dubos, Matthieu Platre, Antoine Martin   +7 more
wiley   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Phenotypic variability of Smallanthus sonchifolius germplasm of Peru

Genetic Resources
Smallanthus sonchifolius (yacon) is a functional food native to the South American Andes. Its tuberous root and leaves are the main parts consumed; however, few studies have been carried out on its phenotypic variability.
Angel Esteban Santa Cruz Padilla, Jorge Luis Vásquez Orrillo, Silvia Yanina Rodríguez López, Araceli Eugenio Leiva, Ricardo Manuel Bardales-Lozano, Juan F. Seminario , Hipolito Murga-Orrillo   +6 more
doaj   +1 more source

The role and implications of mammalian cellular circadian entrainment

FEBS Letters, EarlyView.
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley   +1 more source

Analysis of passport data of Sechium spp. from the Mexican chayote genebank in Huatusco, Veracruz

Genetic Resources
Chayote (Sechium spp.) (Cucurbitaceae) is a Mesoamerican genus, with Mexico being the primary centre of biodiversity for four species: Sechium compositum, S. chinantlense, S. hintonii and S. edule.
Jorge Cadena-Iñiguez, Luis Angel Barrera­-Guzmán, Víctor Manuel Cisneros-Solano, Carlos Hugo Avendaño-Arrazate, María de Lourdes C Arévalo-Galarza, Kazuo N Watanabe, Jorge D Cadena-Zamudio   +6 more
doaj   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source