Results 81 to 90 of about 8,942,317 (309)

Venetoclax‐Based Therapy as a Bridge to Hematopoietic Stem Cell Transplantation in Relapsed or Refractory Pediatric Acute Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Relapsed and/or refractory (R/R) pediatric acute leukemia carries a dismal prognosis, largely driven by chemoresistance to conventional salvage therapy. The BH3‐mimetic venetoclax, combined with chemotherapy or hypomethylating agents, has demonstrated efficacy in small clinical trials.
Katherine S. Colman, Deborah Meyran, Vajiranee Malalasekera, Heather Weerdenburg, Janine Campbell, Rachel Conyers, Stacie Wang, Hannah Walker, Seong Lin Khaw, Diane Hanna   +9 more
wiley   +1 more source

Language, Culture, and Cancer: Qualitative Insights Into Communication Disparities Among Spanish‐Speaking Caregivers of Children With Cancer

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Latino children are projected to make up nearly one‐third of United States (US) children by 2060, and many of their caregivers speak Spanish. Prior survey research has documented communication difficulties for Spanish‐speaking caregivers of children with cancer, but contemporary qualitative data are limited.
Jenny Ruiz, Alejandra Curbelo‐Paz, Sonia Morales, Elizabeth Contreras, Amy Houtrow, Scott H. Maurer, Judy C. Chang   +6 more
wiley   +1 more source

Sleep Phenotypes, Genetic Susceptibility, and Risk of Obesity in Patients With Type 2 Diabetes: A National Prospective Cohort Study

Journal of Diabetes
Background To determine the associations between sleep phenotypes and the risks of specific obesity types and weight gain in patients with type 2 diabetes (T2D), especially in different genetic risk groups.
Lei Xi, Li Li, Songbo Fu, Yuancheng Dai, Juan Shi, Yanmei Yu, Ying Peng, Hongmei Qiu, Jinsong Kuang, Hongyun Lu, Huige Shao, Chunlei Yuan, Xiaohu Wang, Ping Zhang, Sheli Li, Yanhui Pan, Ling Hu, Zhigang Zhao, Yunxia Chen, Jian Kuang, Yi Shu, Jinhua Qian, Qibin Mao, Jieji Zhang, Yan Liu, Hong Yang, Zhaoli Yan, Weici Xie, Qian Zhang, Ping Zhang, Hongji Wu, Ling Gao, Yongjun Jin, Ning Xu, Chaoyang Xu, Xiaohui Sun, Zhimin Feng, Qing Zhang, Lin Li, Guang Ning, Yifei Zhang, Yanan Cao, Weiqing Wang   +42 more
doaj   +1 more source

Biphasic Clinical Course of Pediatric Cytomegalovirus‐Associated Immune Thrombocytopenia: Early Poor Treatment Response but Favorable Long‐Term Outcomes

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Cytomegalovirus (CMV) is a recognized trigger of immune thrombocytopenia (ITP); however, its incidence and impact on disease course in children remain controversial. Therefore, we aimed to characterize the clinical course of pediatric patients with CMV‐associated ITP.
Oded Gilad, Ohad Atia, Osama Tanous, Dafna Brik Simon, Michal Dvori, Miriam Cohen, Tracie A. Goldberg, Efraim Bilavsky, Joanne Yacobovich, Orna Steinberg‐Shemer   +9 more
wiley   +1 more source

Genetic influences on exercise participation in 37.051 twin pairs from seven countries [PDF]

, 2006
Background A sedentary lifestyle remains a major threat to health in contemporary societies. To get more insight in the relative contribution of genetic and environmental influences on individual differences in exercise participation, twin samples from ...
Hunkin, J, Boomsma, Dorret I, Spector Tim D., Kaprio J, Nicholas G. Martin, Martin NG, Harris, Jennifer R., de Geus, Eco J. C, Belinda K. Cornes, Rose, Richard J., Eco J. C. De Geus, Stubbe JH, Dorret I. Boomsma, Richard J, Harris JR, Stubbe Janine H., Kyvik, KO, Rose RJ, Pedersen, Nancy L., Martin, N.G., de Geus EJ, Tim D Spector, de Geus Eco J.C., Boomsma, Dorret I., Pedersen, Nancy L, Nancy L Pedersen, Cornes, Belinda K, Kaprio, Jaakko, Skytthe A, Martin, Nicholas G., Stubbe, Janine H., Kyvik, K., Vink, JM, Hunkin Janice, Rose, Richard J, Rose, RJ, Jacqueline M. Vink, Vink JM, Skytthe, Axel, Pedersen NL, Dorret I Boomsma, Vink, J.M., Hunkin, J., Vink, Jacqueline M., Kujala, Urho M, Jennifer R Harris, Kyvik KO, Boomsma DI, Boomsma, DI, Kujala UM, Cornes, Belinda K., Kaprio, J., Kyvik, Kirsten O., Richard J Rose, Jennifer R. Harris, Axel Skytthe, Spector, Tim D, Nancy L. Pedersen, Rose Richard J., Kujala, UM, Stubbe, JH, Skytthe, A, Eco J C de Geus, Kirsten O. Kyvik, Kyvik Kirsten O., Harris Jennifer R., Janice Hunkin, Boomsma Dorret I., Skytthe Axel, Vink Jacqueline M., Spector TD, Kirsten O Kyvik, Kujala, U., Kaprio Jaakko, Stubbe, Janine H, Pedersen, N.L., Martin, NG, Kujala, Urho M., Cornes Belinda K., Urho M. Kujala, Harris, Jennifer R, Spector, T.D., Jaakko Kaprio, Pedersen, NL, Stubbe, J.H., Martin Nicholas G., Cornes BK, Tim D. Spector, de Geus, E.J.C.; id_orcid, de Geus, EJ, Harris, JR, Vink, Jacqueline M, Kyvik, Kirsten O, Cornes, B., Belinda K Cornes, Urho M Kujala, Rose, R.J., Spector, Tin D., Skytthe, A., Pedersen Nancy L., Martin, Nicholas G, Kaprio, J, Janine H Stubbe, Cornes, BK, De Geus, Eco J. C., Hunkin J, Nicholas G Martin, Jacqueline M Vink, Spector, TD, Hunkin, Janice, Boomsma, D.I.; id_orcid, Harris, J.R., Janine H. Stubbe, Kujala Urho M.   +113 more
core   +2 more sources

The Contribution of Genetic Risk and Lifestyle Factors in the Progression of Diabetes to Diabetic Kidney Disease: A Prospective Cohort Study

Journal of Diabetes
Aims Diabetes is a global public health crisis, especially when it is accompanied by microvascular complications such as diabetic kidney disease (DKD).
Yujiao Wang, Chunyang Li, Nongbu Cili, Jing Chen, Huazhen Yang, Ping Fu, Xiaoxi Zeng   +6 more
doaj   +1 more source

Bone Mineral Density After Contemporary Treatment for Acute Lymphoblastic Leukaemia: A Matched Cross‐Sectional Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Reduced bone mineral density (BMD) has been reported in survivors of childhood and young adult acute lymphoblastic leukaemia (ALL); however, data from cohorts treated with contemporary protocols and including matched controls remain limited.
Karen Schow Jensen, Mette Tiedemann Skipper, Niels Holtum Birkebæk, Kjeld Schmiegelow, Thomas Leth Frandsen, Bente Langdahl, Rikke Beck Jensen, Asger Roer Pedersen, Christian Mølgaard, Liv Andrés‐Jensen, Birgitte Klug Albertsen   +10 more
wiley   +1 more source

Psychosis Endophenotypes: A Gene-Set-Specific Polygenic Risk Score Analysis [PDF]

, 2023
BACKGROUND AND HYPOTHESIS: Endophenotypes can help to bridge the gap between psychosis and its genetic predispositions, but their underlying mechanisms remain largely unknown.
Genetic Risk and Outcome of Psychosis (GROUP) Study, Brain, Onderzoek   +2 more
core  

Parents of Youth With Cancer Report on Their Psychosocial Care: iSTEPPP Survey Finds Alignment and Gaps With Standards

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background The Standards for Psychosocial Care for Children with Cancer and Their Families guide the provision of comprehensive psychosocial care. Parallel to research characterizing implementation of the Standards from the perspective of providers, this study examines implementation of the Standards from the perspective of parents of youth ...
Emily M. Pariseau, Kimberly Buff, Michele A. Scialla, Kimberly S. Canter, Lori Wiener, Victoria Sardi‐Brown, Julia B. Tager, Kamyar Arasteh, Anne E. Kazak   +8 more
wiley   +1 more source

Predictors of Current DSM-5 PTSD Diagnosis and Symptom Severity Among Deployed Veterans: Significance of Predisposition, Stress Exposure, and Genetics

Neuropsychiatric Disease and Treatment, 2020
Yirui Hu,1 Xin Chu,2 Thomas G Urosevich,3 Stuart N Hoffman,4 H Lester Kirchner,1 Richard E Adams,5 Ryan J Dugan,6 Joseph J Boscarino,7 Weixing Shi,2 Carrie A Withey,6 Charles R Figley,8 Joseph A Boscarino6 1Biomedical and Translational Informatics ...
Hu Y, Chu X, Urosevich TG, Hoffman SN, Kirchner HL, Adams RE, Dugan RJ, Boscarino JJ, Shi W, Withey CA, Figley CR, Boscarino JA   +11 more
doaj