Results 221 to 230 of about 445,590 (261)

Strong genetic effect on gout revealed by genetic risk score from meta-analysis of two genome-wide association studies. [PDF]

Hum Cell
Nakayama A, Kawamura Y, Nakatochi M, Toyoda Y, Nakajima M, Maehara K, Kirihara M, Shimizu S, Matsuo K, Matsuo H, Japan Gout Genomics Consortium (Japan Gout).   +10 more
europepmc   +1 more source

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

Cholesterol associated genetic risk score and acute coronary syndrome in Czech males. [PDF]

Mol Biol Rep
Hubacek JA, Adamkova V, Lanska V, Staněk V, Mrázková J, Gebauerová M, Kettner J, Kautzner J, Pitha J.   +8 more
europepmc   +1 more source

Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer

Aging and Cancer, EarlyView.
Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss, Alexis C. Wardell, Allison M. Deal, Kirsten A. Nyrop, Allison Ross, Yara G. Abdou, Jeffrey D. Aldrich, Lisa A. Cary, E. Claire Dees, Katherine E. Reeder‐Hayes, Emily M. Ray, Natalia Mitin, Denis Tsygankov   +12 more
wiley   +1 more source

Combined Serologic and Genetic Risk Score and Prognostication of Phospholipase A2 receptor-Associated Membranous Nephropathy. [PDF]

Clin J Am Soc Nephrol
Hu X, Xu J, Wang W, Liu L, Jing Y, Gao C, Yu X, Li Y, Lin L, Tong J, Weng Q, Pan X, Zhang W, Ren H, Li G, Kiryluk K, Chen N, Xie J.   +17 more
europepmc   +1 more source

Femoral neck width genetic risk score is a novel independent risk factor for hip fractures. [PDF]

J Bone Miner Res
Tobias JH, Nethander M, Faber BG, Heppenstall SV, Ebsim R, Cootes T, Lindner C, Saunders FR, Gregory JS, Aspden RM, Harvey NC, Kemp JP, Frysz M, Ohlsson C.   +13 more
europepmc   +1 more source

A Novel Interaction between a 23-SNP Genetic Risk Score and Monounsaturated Fatty Acid Intake on HbA1c Levels in Southeast Asian Women. [PDF]

Nutrients
Sekar P, Aji AS, Ariyasra U, Sari SR, Tasrif N, Yani FF, Lovegrove JA, Sudji IR, Lipoeto NI, Vimaleswaran KS.   +9 more
europepmc   +1 more source

Genetic distance and ancestry proportion modify the association between maternal genetic risk score of type 2 diabetes and fetal growth. [PDF]

Hum Genomics
Habtewold TD, Wijesiriwardhana P, Biedrzycki RJ, Tekola-Ayele F.   +3 more
europepmc   +1 more source

Type 1 Diabetes Genetic Risk Score classifies diabetes subtypes in Indians: Impact of HLA diversity on the lower discriminative ability

Sankareswaran A, Kunte P, Fraser DP, Shaik M, Weedon MN, Oram RA, Yajnik CS, Chandak GR.   +7 more
europepmc   +1 more source