Results 191 to 200 of about 730,444 (266)

Autoencoders decode polyunsaturated fatty acid metabolism with strong genetic architecture in cancer risk. [PDF]

EBioMedicine
Liu W, Gao H, Qian K.
europepmc   +1 more source

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

FEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia, Masahiro Kimura, Daisuke Kurimoto, Atsushi Sato   +3 more
wiley   +1 more source

"Methodological Constraints and Interpretive Overreach in ESR1-Breast Cancer Association Studies: A Critical Appraisal". [PDF]

Health Sci Rep
Tahir I, Shahbaz H.
europepmc   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

Moving Mendelian Randomization From Traditional Risk Factors to Molecular Targets for Drug Development and Clinical Trials in Nephrology. [PDF]

Kidney Int Rep
Berube AJ, Yu E, Gaheer PS, Lanktree MB.
europepmc   +1 more source

Unraveling gene interaction networks in colorectal cancer and inflammatory bowel disease via a novel hybrid radial basis function network. [PDF]

Sci Rep
Kırkık D, Bulut F.
europepmc   +1 more source

Incisional Hernia Development: Wound Healing Gone Wrong? [PDF]

Wound Repair Regen
Abbas AA, Gunning P, Chintapatla S, Kröger R.   +3 more
europepmc   +1 more source

Alzheimer's disease prediction via an explainable CNN using genetic algorithm and SHAP values. [PDF]

PLoS One
Zahedipour M, Saniee Abadeh M, Shojaei S.   +2 more
europepmc   +1 more source

Radiomics and Machine Learning in Diagnostics of Glial Brain Tumors: a Systematic Review and Meta-Analysis. [PDF]

Sovrem Tekhnologii Med
Danilov GV, Agrba SB, Strunina YV, Shevchenko AM, Konakova TA, Shugay SV, Batalov AI, Pronin IN.   +7 more
europepmc   +1 more source

Editorial: Prevention and treatment of urolithiasis: innovation and novel techniques. [PDF]

Front Surg
Yuen SKK, Xiao B, Somani B.
europepmc   +1 more source