Results 41 to 50 of about 1,723,083 (327)

Compatibility of Breeding Techniques in Organic Systems [PDF]

open access: yes, 2017
Introduction The rapid development of genetic engineering techniques is leading to a level of genetic disruption never experienced before. In order to safeguard organic integrity and to ensure organic food will continue to meet the highest consumer ...

core  

A new control technique for active power filters using a combined genetic algorithm/conventional analysis [PDF]

open access: yes, 2002
In this paper, the computational problems associated with the optimization techniques used to evaluate the switching patterns for controlling variable-characteristics active power filters are presented and critically analyzed.
Darwish, MK, El-Habrouk, M
core   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Use of genetic algorithms and gradient based optimization techniques for calcium phosphate precipitation [PDF]

open access: yes, 2004
Phase equilibrium computations constitute an important problem for designing and optimizing crystallization processes. The Gibbs free energy is generally used as an objective function to find phase amount and composition at equilibrium. In such problems,
C. Azzaro-Pantel   +11 more
core   +1 more source

Plasmodium falciparum gametogenesis essential protein 1 (GEP1) is a transmission‐blocking target

open access: yesFEBS Letters, EarlyView.
This study shows Plasmodium falciparum GEP1 is vital for activating sexual stages of malarial parasites even independently of a mosquito factor. Knockout parasites completely fail gamete formation even when a phosphodiesterase inhibitor is added. Two single‐nucleotide polymorphisms (V241L and S263P) are found in 12%–20% of field samples.
Frederik Huppertz   +5 more
wiley   +1 more source

4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase in malaria parasites and enhances atovaquone efficacy

open access: yesFEBS Letters, EarlyView.
Atovaquone is an antimalarial requiring potentiation for sufficient efficacy. We pursued strategies to enhance its activity, showing that 4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase, decreasing ubiquinone biosynthesis. Since atovaquone competes with ubiquinol in mitochondria, 4‐nitrobenzoate facilitates its action, potentiating ...
Ignasi Bofill Verdaguer   +7 more
wiley   +1 more source

Genotyping Escherichia coli O157:H7 strains isolated from cattle and small ruminants in Fars province (Iran) using Enterobacterial Repetitive Intergenic Consensus PCR Analysis

open access: yesRevue d’Elevage et de Médecine Vétérinaire des Pays Tropicaux
Background: Shiga toxin-producing Escherichia coli (STEC) strains are bacteria that cause gastrointestinal illnesses in humans. The strain E. coli O157:H7 diarrhea, hemorrhagic colitis, and hemolytic-uremic syndrome in humans. Cattle and small ruminants
Sedigheh Mokhtari   +4 more
doaj   +1 more source

Investigating the population structure of Xanthomonas citri pv. citri. Which molecular markers to use to distinguish between low polymorphic bacterial populations? : [P-96] [PDF]

open access: yes, 2010
Comprehensive knowledge of pathogen population structures is crucial to understand the epidemiology and history of infectious diseases, but such data is largely unavailable for plant pathogenic bacteria.
Bui Thi Ngoc, Lan   +3 more
core  

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

MLPA in the initial genetic screening of patients with acute myeloid leukemia

open access: yesRomanian Journal of Internal Medicine
This study aimed to assess the effectiveness of multiplex ligase-dependent probe amplification (MLPA) in the initial genetic screening of patients with acute myeloid leukemia (AML) since current risk stratification and clinical management depend on ...
Yahya Dinnar   +4 more
doaj   +1 more source

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