Results 41 to 50 of about 1,755,519 (297)

MLPA in the initial genetic screening of patients with acute myeloid leukemia

Romanian Journal of Internal Medicine
This study aimed to assess the effectiveness of multiplex ligase-dependent probe amplification (MLPA) in the initial genetic screening of patients with acute myeloid leukemia (AML) since current risk stratification and clinical management depend on ...
Yahya Dinnar, Hachmeriyan Mari, Ruseva Tsanka, Chervenkov Trifon, Micheva Ilina   +4 more
doaj   +1 more source

Why and When Are Evidence‐Based Interventions Adopted in Paediatric Supportive Care? A Qualitative Exploration of the Determinants of Photobiomodulation Implementation

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Oral mucositis is a common and debilitating side effect of childhood cancer and stem cell transplant treatments. It affects the quality of life of children and young people (CYP) and places a strain on services. Photobiomodulation is recommended for oral mucositis prevention in international guidance but is poorly implemented in UK ...
Claudia Heggie, Kara A. Gray‐Burrows, Peter F. Day, Bob Phillips, Carl A. Thompson   +4 more
wiley   +1 more source

Auxanographic Techniques in Biochemical Genetics [PDF]

Journal of General Microbiology, 1949
SUMMARY: Details are given of the ‘auxanographic’ method for identifying growthfactor requirements of micro-organisms, and particularly of mutant strains differing from a parent strain in having additional growth-factor requirements. Cells are distributed in a nutritionally deficient agar medium which is allowed to set in a Petri dish.
openaire   +2 more sources

Personalized Selumetinib Dosing in Pediatric Neurofibromatosis Type 1: Insights From a Pilot Therapeutic Drug Monitoring Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate selumetinib exposure using therapeutic drug monitoring (TDM) in pediatric patients with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PN), assess interpatient pharmacokinetic variability, and explore the relationship between drug exposure, clinical response, and adverse effects.
Janka Kovács, Zoltán Köllő, Balázs Gellért Karvaly, Mahmoud Obeidat, Rita Nagy, Péter Hegyi, Brigitta Teutsch, Eszter Tuboly, Miklós Garami   +8 more
wiley   +1 more source

Sirolimus for Extracranial Arteriovenous Malformations: A Scoping Review of the Evidence in Syndromic and Non‐Syndromic Cases

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Arteriovenous malformations (AVMs) are rare, high‐flow, vascular anomalies that can occur either sporadically or as part of a genetic syndrome. AVMs can progress with serious morbidity and even mortality if left unchecked. Sirolimus is an mTOR inhibitor that is effective in low‐flow vascular malformations; however, its role in AVMs is unclear.
Will Swansson, Ingrid Winship, Gary Hammerschlag, Laura Scardamaglia   +3 more
wiley   +1 more source

Optimisation of the weighting functions of an H_∞ controller using genetic algorithms and structured genetic algorithms

, 2008
In this paper the optimisation of the weighting functions for an H_∞ controller using genetic algorithms and structured genetic algorithms is considered. The choice of the weighting functions is one of the key steps in the design of
Alfaro-Cid, E., McGookin, E.W., Murray-Smith, D.J.   +2 more
core   +1 more source

Genotyping Escherichia coli O157:H7 strains isolated from cattle and small ruminants in Fars province (Iran) using Enterobacterial Repetitive Intergenic Consensus PCR Analysis

Revue d’Elevage et de Médecine Vétérinaire des Pays Tropicaux
Background: Shiga toxin-producing Escherichia coli (STEC) strains are bacteria that cause gastrointestinal illnesses in humans. The strain E. coli O157:H7 diarrhea, hemorrhagic colitis, and hemolytic-uremic syndrome in humans. Cattle and small ruminants
Sedigheh Mokhtari, Yahya Tahamtan, Mohammad Kargar, Keyvan Tadayon, Elham Moazamian   +4 more
doaj   +1 more source

Evaluating the Utility of Paired Tumor and Germline Targeted DNA Sequencing for Pediatric Oncology Patients: A Single Institution Report

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate the diagnostic yield and utility of universal paired tumor–normal multigene panel sequencing in newly diagnosed pediatric solid and central nervous system (CNS) tumor patients and to compare the detection of germline pathogenic/likely pathogenic variants (PV/LPVs) against established clinical referral criteria for cancer ...
Natalie Waligorski, Rebecca Ronsley, Shannon M. Stasi, Jeffrey Stevens, Erin R. Rudzinski, Christina M. Lockwood, Sarah E. S. Leary, Bonnie L. Cole, Michelle A. Ting, Vera Paulson   +9 more
wiley   +1 more source

Compatibility of Breeding Techniques in Organic Systems [PDF]

, 2017
Introduction The rapid development of genetic engineering techniques is leading to a level of genetic disruption never experienced before. In order to safeguard organic integrity and to ensure organic food will continue to meet the highest consumer ...

core  

Automated segmentation of tissue images for computerized IHC analysis [PDF]

, 2010
This paper presents two automated methods for the segmentation ofimmunohistochemical tissue images that overcome the limitations of themanual approach aswell as of the existing computerized techniques.
A. Acquaviva, Borad, Boykov, Brey, Cheng, Cheng, Cregger, Cualing, Di Cataldo, Divito, E. Ficarra, E. Macii, Ficarra, Ficarra, Fuchs, Gonzalez, Gudla, Huang, Jacob, Jain, Kim, Lacroix-Triki, Landini, Long, Lopez, Luck, Markiewicz, Masmoudi, Matula, Mukherjee, Naik, Pinidiyaarachchi, Ruifrok, Ruifrok, S. Di Cataldo, Statnikov, Taneja, Theodosiou, Twellmann, Wang, Wolff, Yang, Zehntner, Zhang   +43 more
core   +1 more source