Results 121 to 130 of about 1,972,073 (332)

Clinical applications of next‐generation sequencing‐based ctDNA analyses in breast cancer: defining treatment targets and dynamic changes during disease progression

Molecular Oncology, EarlyView.
Circulating tumor DNA (ctDNA) offers a possibility for different applications in early and late stage breast cancer management. In early breast cancer tumor informed approaches are increasingly used for detecting molecular residual disease (MRD) and early recurrence. In advanced stage, ctDNA provides a possibility for monitoring disease progression and
Eva Valentina Klocker, Samantha Hasenleithner, Rupert Bartsch, Simon P. Gampenrieder, Daniel Egle, Christian F. Singer, Gabriel Rinnerthaler, Michael Hubalek, Katja Schmitz, Zsuzsanna Bago‐Horvath, Andreas Petzer, Sonja Heibl, Ellen Heitzer, Marija Balic, Michael Gnant   +14 more
wiley   +1 more source

Genetic counselling resources in non-english languages: A scoping review

PEC Innovation, 2023
Objective: Genetic counselling is essential for individuals seeking genetic or genomic testing. Whereas innovative strategies for GC delivery are being explored to meet the growing demand on the clinical genetics workforce, it is essential to consider ...
Rhea Beauchesne, Patricia Birch, Alison M. Elliott   +2 more
doaj  

DATA FOR TESTING FOR GENETIC LINKAGE ON 500 PAIRS OF SIBS [PDF]

, 1941
William C. Boyd, Lyle G. Boyd
openalex   +1 more source

Impact of the public/private mix of health insurance on genetic testing [PDF]

Privacy of information is a central concern in the debate about genetic testing. Two types of social inefficiencies may occur when information about prevention and test status is private; genetic testing may not be done when it is socially efficient and ...
Hoel, Michael, Iversen, Tor
core  

Circulating tumor cells in metastatic breast cancer patients treated with immune checkpoint inhibitors – a biomarker analysis of the ALICE and ICON trials

Molecular Oncology, EarlyView.
In this explorative biomarker analysis, we assessed serial sampling of circulating tumor cells (CTCs) with CellSearch in two randomized trials testing immune checkpoint inhibitors (ICIs) in metastatic breast cancer. Our data demonstrate a prognostic potential of CTCs, most apparent 4 weeks into ICI therapy.
Nikolai Kragøe Andresen, Andreas Hagen Røssevold, Elin Borgen, Cecilie Bendigtsen Schirmer, Bjørnar Gilje, Øystein Garred, Jon Lømo, Marius Stensland, Oddmund Nordgård, Ragnhild Sørum Falk, Randi R. Mathiesen, Hege G. Russnes, Jon Amund Kyte, Bjørn Naume   +13 more
wiley   +1 more source

Predicting cerebral infarction and transient ischemic attack in healthy individuals and those with dysmetabolism: a machine learning approach combined with routine blood tests

Scientific Reports
Ischemic cerebral infarction is the most prevalent type of stroke, causing significant disability and death worldwide. Transient ischemic attack (TIA) is a strong predictor of subsequent stroke.
Yunyun Yang, Lindan Huang, Ying Gu, Zhicheng Wang, Shuai Liu, Qun Chen, Wanshan Ning, Guolin Hong   +7 more
doaj   +1 more source

The genetic background of Southern Iranian couples before marriage

Balkan Journal of Medical Genetics, 2016
Genetic service for couples plays an increasingly important role in diagnosis and risk management. This study investigated the status of consanguinity and the medical genetic history (effectiveness and coverage of medical genetic services) in couples ...
Nariman A, Sobhan MR, Savaei M, Aref-Eshghi E, Nourinejad R, Manoochehri M, Ghahremani S, Daliri F, Daliri K   +8 more
doaj   +1 more source

A CRITICAL TEST OF A CURRENT THEORY OF GENETIC RECOMBINATION IN BACTERIOPHAGE [PDF]

, 1962
C M Steinberg, R. S. Edgar
openalex   +1 more source

Clustering and Classification of Genetic Data Through U-Statistics [PDF]

arXiv, 2016
Genetic data are frequently categorical and have complex dependence structures that are not always well understood. For this reason, clustering and classification based on genetic data, while highly relevant, are challenging statistical problems. Here we consider a highly versatile U-statistics based approach built on dissimilarities between pairs of ...
arxiv  

Genetic Monitoring in the Workplace: A Tool Not a Solution [PDF]

, 1999
The authors differentiate between genetic monitoring and screening, and discuss the potential risks and benefits of predictive testing ...
Jablonski, Richard, Musham, Catherine, Trettin, Lillian   +2 more
core   +2 more sources