Results 121 to 130 of about 17,080,653 (424)

Can Genetic Testing Identify Talent for Sport?

Genes, 2019
Elite athlete status is a partially heritable trait, as are many of the underpinning physiological, anthropometrical, and psychological traits that contribute to elite performance.
C. Pickering, J. Kiely, J. Grgic, A. Lucia, J. Del Coso   +4 more
semanticscholar   +1 more source

Identification of functional and diverse circulating cancer‐associated fibroblasts in metastatic castration‐naïve prostate cancer patients

Molecular Oncology, EarlyView.
Cancer‐associated fibroblasts (CAFs) promote cancer growth, invasion (metastasis), and drug resistance. Here, we identified functional and diverse circulating CAFs (cCAFs) in patients with metastatic prostate cancer (mPCa). cCAFs were found in higher numbers and were functional and diverse in mPCa patients versus healthy individuals, suggesting their ...
Richell Booijink, Leon W. M. M. Terstappen, Eshwari Dathathri, Khrystany Isebia, Jaco Kraan, John Martens, Ruchi Bansal   +6 more
wiley   +1 more source

Genetic testing in children

Indian Pediatrics, 2013
Increasing availability of DNA based tests in clinical practice has lead to widespread debate on the ethical issues involved. The wider usage of these tests in children has raised many questions regarding the ethics, validity of the request and its effects on childs psychosocial well-being.
Shubha R. Phadke, Mamatha Gowda
openaire   +3 more sources

Single cell gel/comet assay: Guidelines for in vitro and in vivo genetic toxicology testing

Environmental and Molecular Mutagenesis, 2000
Atthe International Workshop on Genotoxicity Test Procedures (IWGTP) held in Washington, DC, March 25–26, 1999, an expert panel met to develop guidelines for the use of the single‐cell gel (SCG)/Comet assay in genetic toxicology. The expert panel reached
R. Tice, E. Agurell, Diana Anderson, B. Burlinson, A. Hartmann, H. Kobayashi, Y. Miyamae, E. Rojas, J. Ryu, Y. Sasaki   +9 more
semanticscholar   +1 more source

Surfaceome: a new era in the discovery of immune evasion mechanisms of circulating tumor cells

Molecular Oncology, EarlyView.
In the era of immunotherapies, many patients either do not respond or eventually develop resistance. We propose to pave the way for proteomic analysis of surface‐expressed proteins called surfaceome, of circulating tumor cells. This approach seeks to identify immune evasion mechanisms and discover potential therapeutic targets. Circulating tumor cells (
Doryan Masmoudi, Jérome Vialaret, Christophe Hirtz, Catherine Alix‐Panabières   +3 more
wiley   +1 more source

NQO1 polymorphism and susceptibility to ischemic stroke in a Chinese population

BMC Medical Genomics
Background Ischemic stroke (IS) is a major cause of death and disability worldwide. Genetic factors are important risk factors for the development of IS.
Min Wang, Ying Shen, Yuan Gao, Huaqiu Chen, Fuhui Duan, Siying Li, Guangming Wang   +6 more
doaj   +1 more source

"And We Will Fight For Our Race!" A Measurement Study of Genetic Testing Conversations on Reddit and 4chan [PDF]

arXiv, 2019
Progress in genomics has enabled the emergence of a booming market for "direct-to-consumer" genetic testing. Nowadays, companies like 23andMe and AncestryDNA provide affordable health, genealogy, and ancestry reports, and have already tested tens of millions of customers.
arxiv  

Clinical applications of next‐generation sequencing‐based ctDNA analyses in breast cancer: defining treatment targets and dynamic changes during disease progression

Molecular Oncology, EarlyView.
Circulating tumor DNA (ctDNA) offers a possibility for different applications in early and late stage breast cancer management. In early breast cancer tumor informed approaches are increasingly used for detecting molecular residual disease (MRD) and early recurrence. In advanced stage, ctDNA provides a possibility for monitoring disease progression and
Eva Valentina Klocker, Samantha Hasenleithner, Rupert Bartsch, Simon P. Gampenrieder, Daniel Egle, Christian F. Singer, Gabriel Rinnerthaler, Michael Hubalek, Katja Schmitz, Zsuzsanna Bago‐Horvath, Andreas Petzer, Sonja Heibl, Ellen Heitzer, Marija Balic, Michael Gnant   +14 more
wiley   +1 more source

MOLECULAR IDENTIFICATION OF ROOT-KNOT NEMATODES MELOIDOGYNE SPP. ISOLATED FROM CUCUMBER FARMS IN DIFFERENT IRAQI REGIONS [PDF]

مجلة الأنبار للعلوم الزراعية
Meloidogyne spp. is one of the most common crop diseases globally. Due to the similarity in morphological features between various Meloidogyne spp., molecular techniques were used to identify their species.
M. R. Abbas, S. M. K. Saadedin, A. A. Suleiman   +2 more
doaj   +1 more source

Conditional inference in cis-Mendelian randomization using weak genetic factors [PDF]

arXiv, 2020
Mendelian randomization is a widely-used method to estimate the unconfounded effect of an exposure on an outcome by using genetic variants as instrumental variables. Mendelian randomization analyses which use variants from a single genetic region (cis-MR) have gained popularity for being an economical way to provide supporting evidence for drug target ...
arxiv