Results 141 to 150 of about 5,304,709 (301)

Genetic testing: picking up the pieces

, 2008
review of Blood Matters: A Journey along the Genetic Frontier, by Masha ...
Kavalier, Fred
core  

Responsibility of genetic testing [PDF]

Genetics in Medicine, 2004
openaire   +2 more sources

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

FEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil, Jeffrey A. Hawkes, Cecilia Blikstad, Pia Lindberg   +3 more
wiley   +1 more source

Genetic testing: A threat to privacy

, 2001
This chapter summarises some of the problems associated with privacy and genetic information in the medical context of genetic testing. It outlines some of the major reasons why legislation is needed to protect our genetic privacy.
Gesche, Astrid H.
core  

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

FEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux, Christian Lévêque, Fodil Azzaz, Marion Sangiardi, Sarosh R Irani, Michael Seagar, Jacques Fantini, Oussama El Far   +7 more
wiley   +1 more source

The Song Remains the Same: Genetic Testing in Advanced Heart Failure. [PDF]

JACC Adv
Kransdorf EP, Masha L.
europepmc   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

FEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos, Antonia Petropoulou, Alexandra Anastogianni, Angelina Bania, Vassilis Stamatakis, Argyris Alexiou, Chi‐Ping Day, Glenn Merlino, Katerina Grafanaki, Constantinos Stathopoulos   +9 more
wiley   +1 more source

Paving the way for integrating genetic testing into clinical care in childhood-onset schizophrenia. [PDF]

Gen Psychiatr
Fernandez A, Auby P, Chaumette B, Laure G, Thümmler S, Askenazy F.   +5 more
europepmc   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Consumer Experiences and Perceptions of Genetic Counseling in Provider-Mediated Genetic Testing. [PDF]

J Genet Couns
Lauro KA, Wong B, Iuliano J, Peo M, Park J, Dent KM, Bradbury AR, Kilbride MK.   +7 more
europepmc   +1 more source