Results 121 to 130 of about 5,531,670 (305)
Scientific ReportsIschemic cerebral infarction is the most prevalent type of stroke, causing significant disability and death worldwide. Transient ischemic attack (TIA) is a strong predictor of subsequent stroke.
Yunyun Yang +7 more
doaj +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Genetic testing: A threat to privacy
, 2001 This chapter summarises some of the problems associated with privacy and genetic information in the medical context of genetic testing. It outlines some of the major reasons why legislation is needed to protect our genetic privacy.
Gesche, Astrid H.
core
Genetic testing in Parkinson's disease
, 2005 Parkinson's disease (PD) is a common neurodegenerative disorder of adulthood characterized clinically by rigidity, bradykinesia, resting tremor, and postural instability.
Aideen McInerney‐Leo +7 more
core +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Myriad genetics: Patent law and genetic testing
, 2003 This paper considers the legal challenges to the legal validity of the patents held by Myriad Genetics in respect of genetic testing for breast cancer and ovarian cancer.
Rimmer, Matthew
core
The knowledge and attitude of family members who have receIved predictive genetic test results for hereditary nonpolyposis colorectal cancer in South Africa [PDF]
, 2005 Includes bibliographical references (leaves 134-145).Predictive genetic testing for hereditary nonpolyposis colorectal cancer (HNPC) has been offered to families with known mutations in South Africa since 1997.
Algar, Ursula
core +1 more source
FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Knowledge, Beliefs, and Attitudes Concerning Genetic Testing Among Young Jordanians
Journal of Multidisciplinary Healthcare, 2019 Zaid Altaany,1 Omar F Khabour,2 Ghaith Al-Taani3 1Department of Basic Medical Sciences, Faculty of Medicine, Yarmouk University, Irbid, Jordan; 2Department of Medical Laboratory Sciences, Jordan University of Science and Technology, Irbid, Jordan ...
Altaany Z, Khabour OF, Al-Taani G
doaj
GWAS on yield-related traits of Pakistani wheat under post-anthesis heat stress
BMC GenomicsHeat stress is a major threat to spring wheat (Triticum aestivum) production in the Indo-Gangetic plains of South Asia, particularly in India and Pakistan.
Shabbir Hussain +8 more
doaj +1 more source