Results 171 to 180 of about 1,824,368 (348)

Choosing Progeny-Tested Holstein Sires That Meet Genetic Goals at Minimum Semen Cost

, 1979
R.D. Shanks, A.E. Freeman
openalex   +1 more source

Genetic test for pyruvate kinase deficiency of Basenjis [PDF]

, 1995
Katharine Μ. Whitney, Clinton D. Lothrop   +1 more
openalex   +1 more source

To (genetic) test or not to test, that is the question [PDF]

Journal of Comparative Effectiveness Research, 2015
openaire   +3 more sources

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

Molecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser, Florian Krumbach, Eyleen Corrales, Geoffroy Andrieux, Christian Preisinger, Franziska Liss, Alexandra Golzmann, Melanie Boerries, Kerstin Becker, Ruth Knüchel, Stefan Garczyk, Bernhard Lüscher   +11 more
wiley   +1 more source

Genetic and Environmental-Based Variability in Secondary Metabolite Leaf Content of Adenostyles alliariae and A. alpina (Asteraceae). A Test of the Resource Availability Hypothesis [PDF]

, 1999
Bernd F. Hägele, Martine Rowell‐Rahier   +1 more
openalex   +1 more source

Pervasive genetic testing

The Lancet, 2018
Thiruchelvam, P, Fisher, C, Leff, DR, Domcheck, S   +3 more
openaire   +5 more sources

Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells

Molecular Oncology, EarlyView.
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu, Dilara Demirci, Sude Eris, Bengisu Dayanc, Ece Cakiroglu, Merve Basol, Merve Uysal, Gulcin Cakan‐Akdogan, Fang Liu, Mehmet Ozturk, Gökhan Karakülah, Serif Senturk   +11 more
wiley   +1 more source

Genetic Tests of the Role of Abf1p in Driving Transcription of the Yeast TATA Box Bindng Protein-encoding Gene,SPT15 [PDF]

, 1998
Stephanie Schroeder, P. Anthony Weil
openalex   +1 more source

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

Molecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau, Hayley S. Smith, Begüm Alural, Claire E. Martin, Laura A. New, Manali Tilak, Sara L. Banerjee, Hannah N. Robeson, Nicolas Bisson, Anne‐Claude Gingras, Jasmin Lalonde, Nina Jones   +11 more
wiley   +1 more source

Diagnosis of malignant hyperthermia: a comparison of the in vitro contracture test with the molecular genetic diagnosis in a large pedigree. [PDF]

, 1996
J M Healy, Kathleen A. Quane, Katherine E. Keating, M Lehane, J.J.A. Heffron, Tommie V. McCarthy   +5 more
openalex   +1 more source