Results 181 to 190 of about 17,080,653 (424)
Impact of the public/private mix of health insurance on genetic testing [PDF]
Privacy of information is a central concern in the debate about genetic testing. Two types of social inefficiencies may occur when information about prevention and test status is private; genetic testing may not be done when it is socially efficient and ...
Hoel, Michael, Iversen, Tor
core
Bayesian Model Comparison in Genetic Association Analysis: Linear Mixed Modeling and SNP Set Testing [PDF]
, 2015 We consider the problems of hypothesis testing and model comparison under a flexible Bayesian linear regression model whose formulation is closely connected with the linear mixed effect model and the parametric models for SNP set analysis in genetic ...
Wen, Xiaoquan
core
A CRITICAL TEST OF A CURRENT THEORY OF GENETIC RECOMBINATION IN BACTERIOPHAGE [PDF]
, 1962 C M Steinberg, R. S. Edgar
openalex +1 more source
Molecular Oncology, EarlyView.This study explores how sepsis affects GC progression by creating an immunosuppressive environment. Our findings reveal that sepsis promotes immune dysregulation, enhancing tumor growth and metastasis. Targeting the PD‐1/PD‐L1 pathway with monoclonal antibodies shows potential for restoring immune function and improving outcomes in cancer patients ...
Yiding Wang +10 more
wiley +1 more source
Modeling and Testing for Joint Association Using a Genetic Random Field Model [PDF]
arXiv, 2013 Substantial progress has been made in identifying single genetic variants predisposing to common complex diseases. Nonetheless, the genetic etiology of human diseases remains largely unknown. Human complex diseases are likely influenced by the joint effect of a large number of genetic variants instead of a single variant. The joint analysis of multiple
arxiv
Genetic Monitoring in the Workplace: A Tool Not a Solution [PDF]
, 1999 The authors differentiate between genetic monitoring and screening, and discuss the potential risks and benefits of predictive testing ...
Jablonski, Richard +2 more
core +2 more sources
Molecular Oncology, EarlyView.VASP was found to be overexpressed in metastatic oral squamous cell carcinoma (OSCC) tissues. Notably, PTTG1‐ and VASP‐deficient OSCC cells demonstrated suppressed metastatic properties by disrupting the interaction between the cytoskeleton and focal adhesion (FAs) in the filopodia region.
Suyeon Park +6 more
wiley +1 more source
Origin of the genetic code: a testable hypothesis based on tRNA structure, sequence, and kinetic proofreading. [PDF]
, 1978 J. J. Hopfield
openalex +1 more source
Clinical practice guidelines for BRCA1 and BRCA2 genetic testing.
European Journal of Cancer, 2021 P. Pujol +53 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.Consensus molecular subtypes (CMS1‐4) have been identified to study colorectal cancer heterogeneity and serve as potential biomarkers. In this study, we developed and evaluated NanoCMSer, a NanoString‐based classifier using 55 genes, optimized for FF and FFPE to facilitate the clinical evaluation of CMS subtyping.
Arezo Torang +10 more
wiley +1 more source