Results 221 to 230 of about 1,972,073 (332)

Myelodysplastic syndrome diagnosed by genetic testing for hereditary cancer: a case report. [PDF]

NPJ Genom Med
Ridd S, Peck L, Bankar A, Charames GS, Lerner-Ellis J, Mahajan R, Sabatini PJB, Wong A, Malcolmson J, Kim RH.   +9 more
europepmc   +1 more source

Thermal proteome profiling and proteome analysis using high‐definition mass spectrometry demonstrate modulation of cholesterol biosynthesis by next‐generation galeterone analog VNPP433‐3β in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Elevated level of cholesterol is positively correlated to prostate cancer development and disease severity. Cholesterol‐lowering drugs, such as statins, are demonstrated to inhibit prostate cancer. VNPP433‐3β interrupts multiple signaling and metabolic pathways, including cholesterol biosynthesis, AR‐mediated transcription of several oncogenes, mRNA 5′
Retheesh S. Thankan, Elizabeth Thomas, Mehari M. Weldemariam, Puranik Purushottamachar, Weiliang Huang, Maureen A. Kane, Yuji Zhang, Nicholas Ambulos, Bi‐Dar Wang, David Weber, Vincent C. O. Njar   +10 more
wiley   +1 more source

Genetic Tests of the Role of Abf1p in Driving Transcription of the Yeast TATA Box Bindng Protein-encoding Gene,SPT15 [PDF]

, 1998
Stephanie Schroeder, P. Anthony Weil
openalex   +1 more source

Reproductive Choices in Haemoglobinopathies: The Role of Preimplantation Genetic Testing. [PDF]

Genes (Basel)
Kakourou G, Vrettou C, Mamas T, Traeger-Synodinos J.   +3 more
europepmc   +1 more source

Elucidating prognostic significance of purine metabolism in colorectal cancer through integrating data from transcriptomic, immunohistochemical, and single‐cell RNA sequencing analysis

Molecular Oncology, EarlyView.
Low expression of five purine metabolism‐related genes (ADSL, APRT, ADCY3, NME3, NME6) was correlated with poor survival in colorectal cancer. Immunohistochemistry analysis showed that low NME3 (early stage) and low ADSL/NME6 (late stage) levels were associated with high risk.
Sungyeon Kim, Myunghee Kang, Soyeon Jeong, Jisup Kim, Kyoung Oh Kim, Won‐Suk Lee, Jeong‐Heum Baek, Jung Ho Kim, Seungyoon Nam   +8 more
wiley   +1 more source

Clinical rationale of genetic testing in dementia. [PDF]

, 1997
Giovanni B. Frisoni, Marco Trabucchi
openalex   +1 more source

Cardiomyopathy genetic testing: insights into demographics, counseling, and cascade screening. [PDF]

Future Cardiol
Bui QM, Silver E, Argiro A, Murray S, Korty L, Silva Enciso J, Urey MA, Chi NC, Hong KN, Adler ED.   +9 more
europepmc   +1 more source

Highly multiplexed digital PCR assay for simultaneous quantification of variant allele frequencies and copy number alterations of KRAS and GNAS in pancreatic cancer precursors

Molecular Oncology, EarlyView.
Combining melting curve analysis enhances the multiplexing capability of digital PCR. Here, we developed a 14‐plex assay to simultaneously measure single nucleotide mutations and amplifications of KRAS and GNAS, which are common driver genes in pancreatic cancer precursors. This assay accurately quantified variant allele frequencies in clinical samples
Junko Tanaka, Tatsuo Nakagawa, Yusuke Ono, Yoshio Kamura, Takeshi Ishida, Hidemasa Kawabata, Kenji Takahashi, Hiroki Sato, Andrew S. Liss, Yusuke Mizukami, Takahide Yokoi   +10 more
wiley   +1 more source

Genetic testing and insurance [PDF]

, 1996
R. J. Skaer
openalex   +1 more source

The value of genetic testing in pediatric and adult ophthalmology. [PDF]

Med Genet
Kellner U, Kellner S, Weinitz S, Farmand G.   +3 more
europepmc   +1 more source