Results 261 to 270 of about 1,948,626 (333)

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

Practice Recommendations for Genetic Testing of Ataxias. [PDF]

open access: yesAnn Clin Transl Neurol
Srinivasan SR   +7 more
europepmc   +1 more source

Cross-border genetic testing

open access: yesOrphanet Journal of Rare Diseases, 2010
Barton David
doaj   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Not all information is equally important: informed consent to genetic testing for hereditary cancer. [PDF]

open access: yesJ Cancer Res Clin Oncol
Thomas P   +9 more
europepmc   +1 more source

Genetic Testing For Alzheimer’s And Long-Term Care Insurance

open access: green, 2010
Donald H. Taylor   +5 more
openalex   +2 more sources

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

Low Yield of Genetic Testing in Serrated Polyposis Syndrome. [PDF]

open access: yesClin Transl Gastroenterol
Upadhye I   +4 more
europepmc   +1 more source

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