Results 261 to 270 of about 1,955,627 (332)
Reproductive aging, preimplantation genetic testing for aneuploidy, and the diameter of blastocysts: does size matter? [PDF]
Wyroba J+4 more
europepmc +1 more source
Male infertility is a known risk factor for the development of testicular cancer. In this paper, we analyzed the expression profile of a microRNA panel by real‐time PCR and validated the results by digital PCR. Experimental and bioinformatics analyses allowed us to identify possible biomarkers able to discern men with a higher risk of developing ...
Carmen Ferrara+14 more
wiley +1 more source
For early diagnosis of young patients with Werner syndrome: Indication for genetic testing. [PDF]
Sato T+25 more
europepmc +1 more source
The authors conducted a retrospective study of 94 patients with advanced cancer who underwent next‐generation sequencing (NGS) gene panel analysis and received targeted treatments when applicable. Results further support evidence indicating that molecular profiling provides clinical benefit.
Michaël Dang+3 more
wiley +1 more source
Early diagnosis of hereditary angioedema in children: genetic testing should be prioritized. [PDF]
Bocquet A+6 more
europepmc +1 more source
Analysis of ESR1 mutations in plasma cell‐free DNA (cfDNA) is highly important for the selection of treatment in patients with breast cancer. Using multiplex‐ddPCR and identical blood draws, we investigated whether circulating tumor cells (CTCs) and cfDNA provide similar or complementary information for ESR1 mutations.
Stavroula Smilkou+11 more
wiley +1 more source
Multi‐omics profiling reveals key factors involved in Ewing sarcoma metastasis
Using a mouse model that recapitulates the spread of tumor cells within the body, we have profiled paired tumors and metastasis samples using a multiomics approach combining different layers of biological information. We identified key genes that drive metastasis in Ewing sarcoma.
Mariona Chicón‐Bosch+11 more
wiley +1 more source
Navigating Genetic Testing in Nephrology: Options and Decision-Making Strategies. [PDF]
Groopman E, Milo Rasouly H.
europepmc +1 more source