Results 201 to 210 of about 1,463,301 (359)

Development of Cardiovascular Disease Therapeutics Using Space Environment: Opportunities and Challenges

Hanggong uju uihakoeji
As research on the unique effects of space environment, especially microgravity and cosmic radiation, on the cardiovascular system is being conducted, research on the development of cardiovascular therapeutics using the space environment is attracting
Hyelim Park, Kyu-Sung Kim
doaj   +1 more source

316. Enhanced Tumor Growth Inhibition of Subcutaneous Neuro-2a Tumors in Immunocompetent Mice by Combinatorial Therapy with Genetically Engineered HSV-1 Expressing MCP-1 and IL-12 [PDF]

, 2002

openalex   +1 more source

Multiplex single‐cell profiling of putative cancer stem cell markers ALDH1, SOX9, SOX2, CD44, CD133 and CD15 in endometrial cancer

Molecular Oncology, EarlyView.
Cancer stem cells are associated with aggressive disease, but a deep characterization of such markers is lacking in endometrial cancer. This study uses imaging mass cytometry to explore putative cancer stem cell markers in endometrial tumors and corresponding organoid models.
Hilde E. Lien, Marta E. Hjelmeland, Hege F. Berg, Rose M. Gold, Kathrine Woie, Lars A. Akslen, Ingfrid S. Haldorsen, Camilla Krakstad   +7 more
wiley   +1 more source

Effects of genetic differences in CYP2C19 status on cure rates of Hericobacter pylori infection by dual rabeprazole/amoxicillin therapy in comparison with dual omeprazole/amoxicillin therapy

, 2000
Takahisa Furuta, Naoshito Shirai, Misako Takashima, Xiao Fang, Hiroyuki Hanai, Kyoichi Ohashi, Takashi Ishizaki   +6 more
openalex   +1 more source

849. Genetic Heterogeneity in Response to Adenovirus Gene Therapy [PDF]

, 2002

openalex   +1 more source

Therapy for Genetic Disease [PDF]

Journal of Medical Genetics, 1992
openaire   +2 more sources

Peripheral blood proteome biomarkers distinguish immunosuppressive features of cancer progression

Molecular Oncology, EarlyView.
Immune status significantly influences cancer progression. This study used plasma proteomics to analyze benign 67NR and malignant 4T1 breast tumor models at early and late tumor stages. Immune‐related proteins–osteopontin (Spp1), lactotransferrin (Ltf), calreticulin (Calr) and peroxiredoxin 2 (Prdx2)–were associated with systemic myeloid‐derived ...
Yeon Ji Park, Jae Won Oh, Hyewon Chung, Jung Won Kwon, Yi Rang Na, Kwang Pyo Kim, Seung Hyeok Seok   +6 more
wiley   +1 more source

Topical miRNA Delivery via Elastic Liposomal Formulation: A Promising Genetic Therapy for Cutaneous Lupus Erythematosus (CLE). [PDF]

Int J Mol Sci
Joseph-Mullol B, Royo M, Preat V, Moliné T, Ferrer B, Aparicio G, Cortés-Hernández J, Solé C.   +7 more
europepmc   +1 more source

High-dose vitamin therapy stimulates variant enzymes with decreased coenzyme binding affinity (increased Km): relevance to genetic disease and polymorphisms [PDF]

, 2002
Bruce N. Ames, Ilan Elson‐Schwab, Eli A. Silver   +2 more
openalex   +1 more source

Stochastic variation in the FOXM1 transcription program mediates replication stress tolerance

Molecular Oncology, EarlyView.
Cellular heterogeneity is a major cause of drug resistance in cancer. Segeren et al. used single‐cell transcriptomics to investigate gene expression events that correlate with sensitivity to the DNA‐damaging drugs gemcitabine and prexasertib. They show that dampened expression of transcription factor FOXM1 and its target genes protected cells against ...
Hendrika A. Segeren, Kathryn A. Wierenga, Frank M. Riemers, Elsbeth A. van Liere, Bart Westendorp   +4 more
wiley   +1 more source