Results 271 to 280 of about 5,467,287 (313)

Genetically Informed Therapy in Leukemia

New England Journal of Medicine, 2013
What can we learn from the study of rare diseases? A lot. Chronic myeloid leukemia (CML) occurs in 3 in 100,000 persons, yet it is perhaps the best example of “bench to bedside” medicine in oncology. The discovery of the signature BCR-ABL translocation found in all CML ushered in an era of molecular diagnostics and targeted therapy with tyrosine kinase
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Genetics of Response to Antiplatelet Therapy

2014
Dual antiplatelet therapy has a major role in the management of acute coronary syndromes (ACS) and following percutaneous coronary intervention (PCI). However, significant variation in pharmacodynamic response to antiplatelet therapy has been demonstrated, especially to clopidogrel.
Mark R, Thomas, Robert F, Storey
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Genetic therapy.

Seminars in interventional cardiology : SIIC, 1998
Vascular gene transfer is the introduction of foreign DNA into host cells within the vessel wall. Expression of recombinant genes within vascular cells has been demonstrated in normal, injured and atherosclerotic arteries. Transfer of genes with biological activity has provided insights into the role of specific genes in normal and pathological states.
R D, Simari, E G, Nabel
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GENETIC AND CELLULAR THERAPIES FOR CEREBRAL INFARCTION

Neurosurgery, 2004
Neurosurgeons, working as surgical scientists, can have a prominent role in developing and implementing genetic and cellular therapies for cerebral ischemia. The rapid emergence of both genetic and cellular therapies for neural regeneration warrants a careful analysis before implementation of human studies to understand the pitfalls and promises of ...
Oszkar, Szentirmai, Bob S, Carter
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Gene Therapy for Genetic Diseases

Human Gene Therapy, 1994
(1989). Gene Therapy for Genetic Diseases. Cancer Investigation: Vol. 7, No. 2, pp. 179-192.
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Emerging Genetic Therapies in Epilepsy

Seminars in Neurology
AbstractAdvances in next-generation sequencing have allowed for genetic characterization of many epilepsies that previously had no known cause. Although having a precise diagnosis has been very helpful for management, counseling, and prognosis, until recently true precision medicine approaches that could have disease-modifying effects have been lacking.
Joseph Sullivan, Veronica Hood
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Genetic Tumor Profiling and Genetically Targeted Cancer Therapy

Seminars in Oncology Nursing, 2011
To discuss how understanding and manipulation of tumor genetics information and technology shapes cancer care today and what changes might be expected in the near future.Published articles, web resources, clinical practice.Advances in our understanding of genes and their regulation provide a promise of more personalized cancer care, allowing selection ...
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Genetic Therapies for Xenotransplantation

Journal of the American College of Surgeons, 1998
S S, Lin, J L, Platt
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Human genetic therapy

Molecular Aspects of Medicine, 1993
J, Harris, K, Sikora
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Therapy of genetic diseases

Postgraduate Medicine, 1980
Therapy of genetic diseases may be attempted at three different levels in the evolution of the disease process. At the first level, after clinical manifestations have appeared, methods are symptomatic and include diet, drugs, surgery, and avoidance of hazardous substances. At the second level, midway between the origin of the disease and the appearance
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